Difference between revisions of "Benefit-risk assessment of fish consumption for Beneris"
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{| {{prettytable}} | {| {{prettytable}} | ||
| − | ! | + | !Background variables |
| − | + | | [[Variable:Socio-economic status]] | [[Variable:Smoking status]] | |
| − | + | |---- | |
| − | + | !Exposure variables | |
| − | | [[Variable:Socio-economic status]] | [[Variable:Smoking status]] | [[Variable:Fish oil intake]] | [[Variable:Selenium intake from fish]] | [[Variable:MeHg intake from fish]] | [[Variable:Iodine intake from fish]] | [[Variable:Intake of PCBs from fish]] | [[Variable:Intake of PCDD/Fs from fish]] | [[Variable: | + | | [[Variable:Fish oil intake]] | [[Variable:Selenium intake from fish]] | [[Variable:MeHg intake from fish]] | [[Variable:Iodine intake from fish]] | [[Variable:Intake of PCBs from fish]] | [[Variable:Intake of PCDD/Fs from fish]] | [[Variable:Domestic fish consumption of a general population]] | [[Variable:Domestic fish consumption of pregnant women]] | [[Variable:Concn. of beneficial nutrients in various fish species]] | [[Variable:Omega-3-fatty acid concn.in various fish species]] |
| − | [[Variable:Exposure-response of PCDD/F intake for dental aberrations risk in children]] | [[Variable:Exposure-response of PCDD/F intake for cancer risk in adults]] | | + | |---- |
| − | [[Variable:Exposure-response of MeHg and Se interaction for IQ change in children]] | [[Variable:Exposure-response of MeHg and Se interaction for MI risk in adults]] | + | !Exposure-response functions |
| − | |---- | + | | [[Variable:Exposure-response of fish oil intake for IQ change in children]] | [[Variable:Exposure-response of fish oil intake for MI risk in adults]] | [[Variable:Exposure-response of Se intake for IQ change in children]] | [[Variable:Exposure-response of Se intake for MI risk in adults]] | [[Variable:Exposure-response of MeHg intake for IQ change in children]] | [[Variable:Exposure-response of MeHg intake for MI risk in adults]] | [[Variable:Exposure-response of iodine intake for IQ change in children]] | [[Variable:Exposure-response of PCB intake for dental aberrations risk in children]] | [[Variable:Exposure-response of PCB intake for cancer risk in adults]] | [[Variable:Exposure-response of PCDD/F intake for dental aberrations risk in children]] | [[Variable:Exposure-response of PCDD/F intake for cancer risk in adults]] | [[Variable:Exposure-response of MeHg and Se interaction for IQ change in children]] | [[Variable:Exposure-response of MeHg and Se interaction for MI risk in adults]] |
| − | + | |---- | |
| − | + | !Health effect variables | |
| − | + | | [[Variable:Intelligence quotience change in children]] | [[Variable:Risk for dental aberrations in children]] | [[Variable:Cancer risk in adults ]] | [[Variable:Myocardial infarction risk in adults]] | [[Omega-3 fatty acid beneficial effects on central nervous system development in chidren]] | [[Variable:Omega-3 fatty acid protection against cancer]] | |
| − | |[[Variable: | ||
| − | | [[Variable: | ||
|} | |} | ||
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{|{{prettytable}} | {|{{prettytable}} | ||
| − | + | | Nutritional benefits and risks of PCDD/F exposure of fish consumption in Finnish children and adults [[Media:Valikaavio_RBA_Fish_PCDDs_A_vs._C_25102007_ak_XML.ANA| Analytica model]] | |
|----- | |----- | ||
| − | | [[ | + | |[[Beneris:Risk assessment of MeHg and n-3 fatty acids in fish]] |
|} | |} | ||
| + | [[Image:Valikaavio_RBA_Fish_PCDDs_A_vs._C_25102007_ak.PNG]] | ||
===Indexes=== | ===Indexes=== | ||
Revision as of 22:56, 8 February 2008
Contents
Scope
Net health effects of fish consumption D↷
Purpose
Net health effects of fish consumption due to intake of beneficial nutrients and constituents and on the other hand, exposure to environmental contaminants taken up by fish. This assessment also evaluates the effects of methyl mercury and omega-3 fatty acids on development of IQ in children.
Boundaries
- Environmental contaminants relevant from the human health point of view and thus included in the assessment are:
- polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F)
- polychlorinated biphenyls (PCB)
- mercury as methyl mercury (MetHg)
- Nutritional constituents relevant from the human health point of view include a wide variety of effects and can be viewed from Benefit-risk assessment of fish and related policy options under title "Health consequences attributable to fish consumption". However, readily usable beneficial constituents with quantitative dose-response information available included in the assessment are:
- omega-3 polyunsaturated fatty acids (PUFA)
- iodine (I)
- selenium (Se)
- European sub-populations included in the assessment:
- Finland
- Ireland
- Spain
- Denmark
- Current situation (BAU)
Scenarios
BAU-type assessment (business-as-usual assessment), i.e. a burden-of-disease assessment with only one decision scenario. D↷
Intended users
Experts, researchers and decision makers in the field of environmental health, anyone interested and concerned with beneficial and hazardous constituents in fish species in the markets.
Participants
Participation basically completely open. Some parts containing original data will be protected.
- Everyone interested
- Beneris researchers (full access to the protected parts)
Definition
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Decision variables
- None at the moment
Indicators
Indicator variables include as stated in the submodels:
- Variable:Intelligence quotience change in children
- Variable:Risk for dental aberrations in children
- Variable:Cancer risk in adults
- Variable:Myocardial infarction risk in adults
Other variables
| Nutritional benefits and risks of PCDD/F exposure of fish consumption in Finnish children and adults Analytica model |
| Beneris:Risk assessment of MeHg and n-3 fatty acids in fish |
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Indexes
| Fish species |
|---|
|
| Nutrients |
|---|
|
Age categorizations were chosen in order to describe health effects of fish consumption in infants (0-2 years, this class includes prenatal period as well), adolescent (2-18 years) and adults (18-55 years).
| Age categories (years) |
|---|
|
