ERF of omega-3 fatty acids on CVD risk in adults
Contents
Scope
ERF of omega-3 fatty acids on CVD risk in adults describes quantitative relationship between exposure to omega-3 fatty acids and risk of cardiovascular disease (CVD) in adults.
Definition
ERF of omega-3 fatty acids on CVD risk in adults can be represented as a random variable or as a constant. It is indexed by variable age. It applies to the last two age categories, i.e. 18-55yr and 55yr+.
Data
Fernandez-Jarne et al. [1] examined the relationship between intake of fish and n-3 PUFA and the risk of first acute myocardial infarction (AMI) in a low risk population from Navarre (Spain). They found that the n-3 PUFA intake has a protective effect on AMI. The adjusted odds ratio (OR) for the second and third tertile of n-3 PUFA intake were 0.44 (95% Cl, 0.21-0.91) and 0.47 (95% Cl, 0.22-1.00), respectively. The trend test was not statistically significant. D↷
Mozaffarian and Rimm [2] estimated that at intakes between 0 and 250 mg/d, the relative risk of coronary heart disease (CHD) death is lower by 14.6% (95% CI: 8% to 21%) per each 100 mg/d of EPA and DHA intake and that at higher intakes ( > 250 mg/d) the risk reduction of 0.0% (95% CI: -0.9% to 0.8%) per each 100 mg/d.
Causality
Unit
Formula
Result
See also
References
- ↑ Fernandez-Jarne E, Garrido FA, Gutierrez AA, Arrillaga CDF, Martinez-Gonzales MA. Dietary intake of n-3 fatty acids and the risk of acute myocardial infarction: a case-control study. (In Spanish) 2002;118:121–5.
- ↑ Mozaffarian D., Rimm E.B., Fish intake, contaminants, and human health. Evaluating the risks and the benefits. (Reprinted) JAMA, 2006. Vol 296, No. 15
