Difference between revisions of "Limit values for intakes of persistent pollutants via food"
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| width="10pt"|Year | | width="10pt"|Year | ||
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| '''0,1 µg/kg bw/d | | '''0,1 µg/kg bw/d | ||
| 2000 | | 2000 | ||
| − | | http://www.nap.edu/openbook.php?record_id=9899&page=11, http://books.nap.edu/openbook.php?isbn=0309071402 | + | | [http://www.nap.edu/openbook.php?record_id=9899&page=11 1], [http://books.nap.edu/openbook.php?isbn=0309071402 2] |
| NRC | | NRC | ||
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| 0,3-1,0 µg/kg bw/d | | 0,3-1,0 µg/kg bw/d | ||
| 1998 | | 1998 | ||
| − | | http://www.nap.edu/openbook.php?record_id=9899&page=72 | + | | [http://www.nap.edu/openbook.php?record_id=9899&page=72 3] |
| Clewell et al. 1998 (meta-analysis or suchlike) | | Clewell et al. 1998 (meta-analysis or suchlike) | ||
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| '''0,1 µg/kg bw/d | | '''0,1 µg/kg bw/d | ||
| 1997 | | 1997 | ||
| − | | http://www.epa.gov/ttn/oarpg/t3/reports/volume1.pdf | + | | [http://www.epa.gov/ttn/oarpg/t3/reports/volume1.pdf 4] |
| U.S.EPA for any person including children & pregnant women | | U.S.EPA for any person including children & pregnant women | ||
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| 0,025-0,06 µg/kg bw/d | | 0,025-0,06 µg/kg bw/d | ||
| 1995 | | 1995 | ||
| − | | http://www.ehponline.org/members/1995/Suppl-6/gibert-full.html | + | | [http://www.ehponline.org/members/1995/Suppl-6/gibert-full.html 5] |
| Gilbert & Grant-Webster 1995 | | Gilbert & Grant-Webster 1995 | ||
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| 0,07 µg/kg bw/d | | 0,07 µg/kg bw/d | ||
| 1993 | | 1993 | ||
| − | | http://www3.interscience.wiley.com/journal/119302473/abstract | + | | [http://www3.interscience.wiley.com/journal/119302473/abstract 6] |
| Stern 1993 | | Stern 1993 | ||
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| − | | http://www3.interscience.wiley.com/journal/119302473/abstract | + | | [http://www3.interscience.wiley.com/journal/119302473/abstract 7] |
| JECFA for adults only | | JECFA for adults only | ||
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| 1990 | | 1990 | ||
| − | | http://www.inchem.org/documents/ehc/ehc/ehc101.htm#SubSectionNumber:10.2.2 | + | | [http://www.inchem.org/documents/ehc/ehc/ehc101.htm#SubSectionNumber:10.2.2 8] |
| The WHO/IPCS for adults only | | The WHO/IPCS for adults only | ||
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'''Table 2.''' Limit values for '''PCDD/F and DL-PCB''' intakes as body weight related concentration units per day set up by various international regulating bodies. | '''Table 2.''' Limit values for '''PCDD/F and DL-PCB''' intakes as body weight related concentration units per day set up by various international regulating bodies. | ||
{| {{prettytable}} | {| {{prettytable}} | ||
| − | | TDI | + | | width="80pt"|TDI |
| − | | t-TWI | + | | width="80pt"|t-TWI |
| − | | PTMI | + | | width="80pt"|PTMI |
| − | | Year | + | | width="10pt"|Year |
| − | | Reference | + | | width="420pt"|Reference |
| − | | Organisation | + | | width="100pt"|Organisation |
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| 1999 | | 1999 | ||
| − | | | + | | http://www.terveysportti.fi/xmedia/duo/duo92005.pdf |
| The Nordic Expert Group | | The Nordic Expert Group | ||
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| 1-4 WHO TEQ pg/kg bw | | 1-4 WHO TEQ pg/kg bw | ||
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|} | |} | ||
| − | :TDI=tolerable daily intake | + | :TDI=tolerable daily intake<ref name="IUPAC"/> |
| − | :t-TWI=temporary tolerable weekly intake | + | :t-TWI=temporary tolerable weekly intake<ref name="IUPAC"/> |
| − | :PTMI=permissible tolerable monthly intake | + | :PTMI=permissible tolerable monthly intake<ref name="IUPAC"/> |
:U.S.EPA=The U.S. Environmental Protection Agency | :U.S.EPA=The U.S. Environmental Protection Agency | ||
:SCF=The Scientific Committee on Food of the European Commission | :SCF=The Scientific Committee on Food of the European Commission | ||
Revision as of 12:17, 3 September 2008
The page includes limit values set up by international advisory and/or governing bodies regulating environmental health issues for intakes of persistent contaminants, organic or inorganic, via food. Contaminants currently included for their limit values are:
- Mercury (Hg) as its organic form, methylmercury (MeHg), the most readily bioaccumulated form
- Dioxins and furans (PCDD/F) and dioxin-like polychlorinated biphenyls (DL-PCBs)
- Polybrominated diphenylethers (PBDEs)
Table 1. Limit values for MeHg intakes as body weight related concentration units per day set up by various international regulating bodies.
| TDI | PTWI | RfD | Year | Reference | Organisation |
| - | - | 0,1 µg/kg bw/d | 2000 | 1, 2 | NRC |
| - | - | 0,3-1,0 µg/kg bw/d | 1998 | 3 | Clewell et al. 1998 (meta-analysis or suchlike) |
| - | - | 0,1 µg/kg bw/d | 1997 | 4 | U.S.EPA for any person including children & pregnant women |
| - | - | 0,025-0,06 µg/kg bw/d | 1995 | 5 | Gilbert & Grant-Webster 1995 |
| - | - | 0,05 µg/kg bw/d | 1995 | - | Gilbert & Grant-Webster 1995, Rice 1992 |
| - | - | 0,07 µg/kg bw/d | 1993 | 6 | Stern 1993 |
| - | 3,3 µg/kg bw | - | 7 | JECFA for adults only | |
| 0,48 µg/kg bw | - | - | 1990 | 8 | The WHO/IPCS for adults only |
- TDI=tolerable daily intake[1]
- PTWI=permissible tolerable weekly intake[1]
- RfD=reference dose[1]
- NRC=The U.S. National Research Council
- U.S.EPA=The U.S. Environmental Protection Agency
- JECHA=the Joint FAO/WHO Expert Committee on Food Additives
- WHO/IPCS=The International Programme on Chemical Safety (IPCS) is a joint venture of the United Nations Environment Programme, the International Labour Organisation, and the World Health Organization
Table 2. Limit values for PCDD/F and DL-PCB intakes as body weight related concentration units per day set up by various international regulating bodies.
- TDI=tolerable daily intake[1]
- t-TWI=temporary tolerable weekly intake[1]
- PTMI=permissible tolerable monthly intake[1]
- U.S.EPA=The U.S. Environmental Protection Agency
- SCF=The Scientific Committee on Food of the European Commission
- JECHA=the Joint FAO/WHO Expert Committee on Food Additives
- WHO=World Health Organisation
- ATSDR=The U.S. Agency for Toxic Substances and Disease Registry
PBDEs
For polybrominated diphenylethers there is currently no limit values available. JECFA (the Joint FAO/WHO Expert Committee on Food Additives) however has given an indicative threshold concentration at 100 µg/kg body weight/day, and concludes that ‘the limited toxicity data suggests that for the more toxic (less brominated) PBDE congeners (eg. BDE-47 and BDE-99) adverse effects would be unlikely to occur at doses of less than approximately 100 µg/kg bw per day’. FSANZ (Food Standards Australia New Zealand) concurs with the JECFA conclusions.[2]
