Difference between revisions of "Myocardial infarction risk in adults in Beneris"

Revision as of 21:52, 8 February 2008

Scope
Myocardial infarction risk in adults describes the remaining lifetime risk of having a myocardial infarction in adults as a result of exposure to methyl mercury, selenium and fish oils through fish consumption in the target European country.

Definition

Myocardial infarction in adults is represented as a function of parent variables and is indexed by variable age. It applies to last two age categories and to adults in general (individuals aged 18 years and older).

Causality

List of parents:

• Variable:Fish oil intake
• Variable:Selenium intake from fish
• Variable:MeHg intake from fish
• Variable:Socio-economic status
• Variable:Smoking status
• Variable:Exposure-response of fish oil intake for MI risk in adults
• Variable:Exposure-response of Se intake for MI risk in adults
• Variable:Exposure-response of MeHg intake for MI risk in adults
• Variable:Exposure-response of MeHg and Se interaction for MI risk in adults

Data

Formula

• the (remaining) lifetime risk of myocardial infarction for adults between 18 and 55 years of age:

MI_risk_18_55yr = 1/(1+e^(-(0.5-0.0006*37*(fatty_acids18_55-16)+0.003*37*(mehg18_55-37)-0.0005*37*(selenium18_55-0.29)-0.03*(socioeconomic_status18_55-8)+ 0.01*37*(smoking_status18_55-2.023)-0.0005*37*37*(mehg18_55-37)*(selenium18_55-0.29))))

• the (remaining) lifetime risk of myocardial infarction for adults older than 55 years:

MI_risk_over55yr = 1/(1+e^(-(0.55-0.0037*20*(fatty_acids55-15)+0.003*20*(mehg55-31)-0.0037*20*(selenium55-0.24)-0.005*(socioeconomic_status55-10)+ 0.03*20*(smoking_status55-2.023)-0.00037*20*20*(mehg55-31)*(selenium55-0.24))))

• the (remaining) lifetime risk of myocardial infarction for adults older than 18 years:

MI_risk = 0.6*MI_risk_18_55yr+0.4*MI_risk_over55yr

Unit

Result