User contributions
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- 16:09, 24 August 2009 (diff | hist) . . (-8) . . Point of departure (current)
- 16:08, 24 August 2009 (diff | hist) . . (+32) . . N POD (Redirecting to Point of departure) (current)
- 16:06, 24 August 2009 (diff | hist) . . (+35) . . Weibull (current)
- 16:05, 24 August 2009 (diff | hist) . . (+35) . . Point of departure
- 16:02, 24 August 2009 (diff | hist) . . (+35) . . Michaelis-menten equation (current)
- 16:01, 24 August 2009 (diff | hist) . . (+35) . . Hill equation (current)
- 15:59, 24 August 2009 (diff | hist) . . (+35) . . Goodness-of-fit (current)
- 15:35, 24 August 2009 (diff | hist) . . (+27) . . Normal distribution
- 14:48, 24 August 2009 (diff | hist) . . (+486) . . N Weighted least squares estimate (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Weighted least squares estimate''' is a parameter estimate obtained by minimizing the sum of squares of observed and esti...) (current)
- 14:46, 24 August 2009 (diff | hist) . . (+446) . . N Weibull (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Weibull''' is a form of a dose-response curve characterized by a relatively shallow slope at low doses that increases sha...)
- 14:44, 24 August 2009 (diff | hist) . . (+336) . . N Variance (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Variance''' is a measure of variability, standard deviation squared.<ref name="WHO report">[http://www.who.int/ipcs/metho...) (current)
- 14:43, 24 August 2009 (diff | hist) . . (+376) . . N Variability (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Variability''' is an observable diversity in biological sensitivity or response, and in exposure parameters.<ref name="WH...) (current)
- 14:40, 24 August 2009 (diff | hist) . . (+427) . . N Validation (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Validation''' is a process by which the reliability and relevance of a particular approach, method, process or assessment...) (current)
- 14:38, 24 August 2009 (diff | hist) . . (+355) . . N Upper-tail probability (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Upper-tail probability''' is the probability that a variable exceeds a specified value.<ref name="WHO report">[http://www...) (current)
- 14:35, 24 August 2009 (diff | hist) . . (+355) . . N Unconstrained dose-response model (New page: {{tool|moderator=Reetta}} <section begin=glossary /> :''' Unconstrained dose-response model''' is no restrictions imposed on the estimates of parameters.<ref name="WHO report">[http://www...) (current)
- 14:33, 24 August 2009 (diff | hist) . . (0) . . Uncertainty factor (current)
- 14:32, 24 August 2009 (diff | hist) . . (+523) . . N Uncertainty factor (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Uncertainty factor''' is a reductive factor by which an observed or estimated no-observed-adverse effect level ([[NOA...)
- 14:28, 24 August 2009 (diff | hist) . . (+783) . . N Toxicokinetics (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Toxicokinetics''' is the process of the uptake of potentially toxic substances by the body, the biotransformation they un...) (current)
- 14:26, 24 August 2009 (diff | hist) . . (+417) . . N Toxicodynamics (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Toxicodynamics''' is the process of interaction of chemical substances with target sites and the subsequent reactions lea...) (current)
- 14:24, 24 August 2009 (diff | hist) . . (+420) . . N Threshold of toxicological concern (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Threshold of toxicological concern''' is an exposure threshold value below which there is a very low probability of an ap...) (current)
- 14:22, 24 August 2009 (diff | hist) . . (+215) . . Threshold (current)
- 14:19, 24 August 2009 (diff | hist) . . (+391) . . N Shape parameter (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Shape parameter''' is the exponent on dose in a dose-response function that dictates the curvature of the functio...) (current)
- 14:17, 24 August 2009 (diff | hist) . . (-94) . . Severity (current)
- 14:16, 24 August 2009 (diff | hist) . . (+470) . . N Severity (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Severity''' is a risk management term. The acceptability of risk depends on scientific data, social, economic, and politi...)
- 14:15, 24 August 2009 (diff | hist) . . (-4) . . Safety factor (current)
- 14:14, 24 August 2009 (diff | hist) . . (+534) . . N Safety factor (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Safety factor''' is a composite (reductive) factor by which an observed or estimated no-observedadverse effect level ([[N...)
- 14:09, 24 August 2009 (diff | hist) . . (+573) . . N Risk characterization (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Risk characterization''' is the qualitative and, wherever possible, quantitative determination, including attendant uncer...)
- 14:06, 24 August 2009 (diff | hist) . . (+427) . . N Risk (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Risk''' is the probability of an adverse effect in an organism, system or (sub)population caused under specified circ...) (current)
- 14:04, 24 August 2009 (diff | hist) . . (+350) . . N Residuals (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Residuals''' are the numerical differences between observed and estimated effects.<ref name="WHO report">[http://www.who....) (current)
- 14:02, 24 August 2009 (diff | hist) . . (+535) . . N Residual variance (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Residual variance''' is the variance in experimental measurements remaining after accounting for the variance due to ...) (current)
- 13:59, 24 August 2009 (diff | hist) . . (+410) . . N Response (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Response''' is a change developed in the state or dynamics of an organism, system or (sub) population in reaction to expo...) (current)
- 13:55, 24 August 2009 (diff | hist) . . (+386) . . N Repeated measures (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Repeated measures''' is a biological endpoint is measured for the same individual or animal at different times (ages).<re...) (current)
- 13:53, 24 August 2009 (diff | hist) . . (+498) . . N Regression analysis (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Regression analysis''' is a statistical process that produces a mathematical function (regression equation) that relates ...) (current)
- 13:50, 24 August 2009 (diff | hist) . . (+423) . . N Rectangular hyperbola (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Rectangular hyperbola''' is a mathematical function of the form y squared equals x squared plus c squared, where x and y ...) (current)
- 13:49, 24 August 2009 (diff | hist) . . (+419) . . N Quasi-likelihood (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Quasi-likelihood''' is a likelihood function that is not totally defined and generally based on only an expression includ...) (current)
- 13:46, 24 August 2009 (diff | hist) . . (+385) . . N Quantile (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Quantile''' is a percentile (cumulative probability) of a distribution that ranges from zero to the 100th percentile.<ref...) (current)
- 13:45, 24 August 2009 (diff | hist) . . (+497) . . N Quantal data (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Quantal data''' is a dichotomous (Binomial) classification where an individual or animal is placed in one of two categori...) (current)
- 13:43, 24 August 2009 (diff | hist) . . (+371) . . N Quadratic term (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Quadratic term''' is a quantity in a mathematical formula that is raised to the second power (squared).<ref name="WHO rep...) (current)
- 13:41, 24 August 2009 (diff | hist) . . (+369) . . N Profile likelihood (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Profile likelihood''' is a plot of the likelihood function versus the estimated value of a parameter.<ref name="WHO repor...) (current)
- 13:39, 24 August 2009 (diff | hist) . . (-4) . . Probit function (current)
- 13:38, 24 August 2009 (diff | hist) . . (+489) . . N Probit function (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Probit function''' are the assumes that the relative probabilities of effects as a function of dose are described by ...)
- 13:35, 24 August 2009 (diff | hist) . . (+398) . . N Probability distribution (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Probability distribution''' is a mathematical description of the relative probabilities of all possible outcomes of a mea...) (current)
- 13:34, 24 August 2009 (diff | hist) . . (+450) . . N Probability (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Probability''' is the proportion (on a scale of 0 to 1) of cases for which a particular event occurs. Zero indicates the ...)
- 13:32, 24 August 2009 (diff | hist) . . (+380) . . N Polynomial (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Polynomial''' is a mathematical function of the sum of a constant, linear term, quadratic term, cubic term, etc.<ref name...) (current)
- 15:18, 21 August 2009 (diff | hist) . . (+46) . . N NOAEL (Redirecting to No-observed-adverse-effect level) (current)
- 15:17, 21 August 2009 (diff | hist) . . (+30) . . N MOS (Redirecting to Margin of safety) (current)
- 15:16, 21 August 2009 (diff | hist) . . (+32) . . N MOE (Redirecting to Margin of exposure) (current)
- 15:15, 21 August 2009 (diff | hist) . . (+41) . . N MLE (Redirecting to Maximum likelihood estimate) (current)
- 15:13, 21 August 2009 (diff | hist) . . (+42) . . N LOEL (Redirecting to Lowest-observed-effect level) (current)
- 15:12, 21 August 2009 (diff | hist) . . (+50) . . N LOAEL (Redirecting to Lowest-observed-adverse-effect level) (current)
- 15:07, 21 August 2009 (diff | hist) . . (0) . . Margin of exposure (current)
- 15:05, 21 August 2009 (diff | hist) . . (+737) . . N Point of departure (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :'''Point of departure (POD)''' is a the point on a dose-response curve established from experimental data, e.g., the [[benchm...)
- 14:59, 21 August 2009 (diff | hist) . . (+453) . . N P-value (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' P-value''' in testing a hypothesis, the probability of a type I error (false positive). The probability that the sample (...) (current)
- 14:56, 21 August 2009 (diff | hist) . . (+337) . . N Ordinal data (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Ordinal data''' is a integers designating the rank, order, or counts.<ref name="WHO report">[http://www.who.int/ipcs/meth...) (current)
- 14:53, 21 August 2009 (diff | hist) . . (+366) . . N Objective function (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Objective function''' is a choice of function that is optimized for maximum likelihood estimation.<ref name="WHO report">...) (current)
- 14:51, 21 August 2009 (diff | hist) . . (+427) . . N Normal distribution (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Normal distribution''' is a mathematical description where a continuous random variable x with a mean μ and a variance ...)
- 14:49, 21 August 2009 (diff | hist) . . (+450) . . N Nonlinear dose-response model (New page: {{tool|moderator=Reetta}} <section begin=glossary /> :''' Nonlinear dose-response model''' is a mathematical relationship that cannot be expressed simply as the change in response being p...) (current)
- 14:47, 21 August 2009 (diff | hist) . . (+579) . . N No-observed-adverse-effect level (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' No-observed-adverse-effect level (NOAEL)''' are the highest concentration or amount of a substance, found by experiment o...) (current)
- 14:44, 21 August 2009 (diff | hist) . . (+520) . . N Negligible risk (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Negligible risk''' is a risk management term. In cases where a quantitative risk estimate has been made, it is any risk l...) (current)
- 14:40, 21 August 2009 (diff | hist) . . (+452) . . N Multinomial (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Multinomial''' are animals or individuals may be classified by more than two (binomial) categories, e.g., in a reproducti...) (current)
- 14:37, 21 August 2009 (diff | hist) . . (+511) . . N Monotonic dose-response (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Monotonic dose-response''' is a dose-response that never decreases as dose increases. A monotonic function may be...) (current)
- 14:34, 21 August 2009 (diff | hist) . . (+428) . . N Mode of action (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Mode of action''' is a series of events that may lead to induction of the relevant end-point of toxicity for which the we...) (current)
- 14:31, 21 August 2009 (diff | hist) . . (+379) . . N Margin of safety (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Margin of safety (MOS)''' is a margin between the reference dose and the actual exposure dose or concentration.<ref name=...) (current)
- 14:28, 21 August 2009 (diff | hist) . . (+457) . . N Margin of exposure (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Margin of exposure (MOE)''' is a ratio of the no-observed-adverse-effect level (NOAEL) for the critical effect to the...)
- 14:24, 21 August 2009 (diff | hist) . . (+455) . . N Michaelis-menten equation (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Michaelis-menten equation''' is a dose-response curve, frequently used for enzyme kinetics, with maximum slope at zero [[...)
- 14:21, 21 August 2009 (diff | hist) . . (+424) . . N Mechanism of action (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Mechanism of action''' is a detailed description of the precise chain of events from the molecular level to gross macrosc...) (current)
- 14:18, 21 August 2009 (diff | hist) . . (+399) . . N Maximum likelihood estimate (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Maximum likelihood estimate (MLE)''' is an estimate of a population parameter most likely to have produced the sample obs...) (current)
- 14:15, 21 August 2009 (diff | hist) . . (+8) . . Lowest-observed-adverse-effect level (current)
- 14:13, 21 August 2009 (diff | hist) . . (+7) . . Lowest-observed-effect level (current)
- 14:10, 21 August 2009 (diff | hist) . . (+637) . . N Lowest-observed-effect level (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Lowest-observed-effect level''' is a the lowest concentration or amount of a substance, found by experiment or observatio...)
- 14:09, 21 August 2009 (diff | hist) . . (+650) . . N Lowest-observed-adverse-effect level (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Lowest-observed-adverse-effect level''' is the lowest concentration or amount of a substance, found by experiment or obse...)
- 14:06, 21 August 2009 (diff | hist) . . (+318) . . N Log transformation (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Log transformation''' is a logarithm of raw data. <ref name="WHO report">[http://www.who.int/ipcs/methods/harmonization/d...) (current)
- 14:04, 21 August 2009 (diff | hist) . . (+403) . . N Lognormal distribution (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Lognormal Distribution''' is a mathematical description where the natural logarithm of a random variable has a [[normal d...) (current)
- 14:00, 21 August 2009 (diff | hist) . . (+457) . . N Logistic model (New page: {{tool|moderator=Reetta}} <section begin=glossary /> :''' Logistic model''' is a sigmoid (S-shaped) function that relates the proportion of individuals with a specified characteristic to ...) (current)
- 13:57, 21 August 2009 (diff | hist) . . (+405) . . N Likelihood function (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Likelihood function''' is a relative probabilities that various values of population parameters would arise from the samp...) (current)
- 13:55, 21 August 2009 (diff | hist) . . (+393) . . N Local maximum (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :''' Local maximum''' is a mathematical solution that maximizes a function in a region that may not be the overall global maxi...) (current)
- 13:52, 21 August 2009 (diff | hist) . . (+439) . . N Linearized multistage model (New page: {{tool|moderator=Reetta}} <section begin=glossary /> :''' Linearized multistage model''' is a dose-response model based on the multistage model of carcinogenesis that is restricted to...) (current)
- 15:06, 17 August 2009 (diff | hist) . . (+393) . . N Linear dose-response model (New page: {{tool|moderator=Reetta}} <section begin=glossary /> :'''Linear dose-response model''' the amount of change in a response is proportional to the amount of change in some function of [[dos...) (current)
- 14:58, 17 August 2009 (diff | hist) . . (-4) . . Likelihood ratio (current)
- 14:58, 17 August 2009 (diff | hist) . . (+478) . . N Likelihood ratio (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :'''Likelihood ratio''' is a ratio of the probability that the observed data arise from a set of model parameters rela...)
- 14:49, 17 August 2009 (diff | hist) . . (0) . . Least squares (current)
- 14:46, 17 August 2009 (diff | hist) . . (+508) . . N Least squares (New page: {{encyclopedia|moderator=Reetta}} <section begin=glossary /> :'''Least squares''' is a statistical procedure that estimates the values of dose-response parameters such that the sum of...)
- 14:27, 17 August 2009 (diff | hist) . . (+149) . . Intercept term (current)
- 14:26, 17 August 2009 (diff | hist) . . (+149) . . Independence (current)
- 14:25, 17 August 2009 (diff | hist) . . (+149) . . Hybrid model (current)
- 14:23, 17 August 2009 (diff | hist) . . (+150) . . Hill equation
- 14:22, 17 August 2009 (diff | hist) . . (+150) . . Hazard identification (current)
- 14:21, 17 August 2009 (diff | hist) . . (+149) . . Goodness-of-fit
- 14:19, 17 August 2009 (diff | hist) . . (+149) . . Generalized estimating equation (current)
- 14:17, 17 August 2009 (diff | hist) . . (+149) . . Gaussian (normal) distribution (current)
- 14:16, 17 August 2009 (diff | hist) . . (+149) . . Gamma distribution (current)
- 14:15, 17 August 2009 (diff | hist) . . (+149) . . Excess risk (current)
- 14:13, 17 August 2009 (diff | hist) . . (+149) . . Estimate (current)
- 14:12, 17 August 2009 (diff | hist) . . (+149) . . EDx (current)
- 14:11, 17 August 2009 (diff | hist) . . (+149) . . Dose-response trend (current)
- 14:10, 17 August 2009 (diff | hist) . . (+149) . . Dose-response model (current)
- 14:09, 17 August 2009 (diff | hist) . . (+149) . . Dose-response assessment (current)
- 14:07, 17 August 2009 (diff | hist) . . (+149) . . Dose-response (current)
- 14:06, 17 August 2009 (diff | hist) . . (+149) . . Dispersion (current)
- 14:04, 17 August 2009 (diff | hist) . . (+149) . . Dichotomous data (current)
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