Talk:Assessment of the health impacts of H1N1 vaccination

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Darm exercise 4

Tasks:

  • Make pairs and select one group A-E (D and E have Finnish material).
  • Look at page Discussion for theoretical and practical advice. Also page op_fi:Keskustelun jälkijäsentäminen may be useful.
  • Look at the two or three links on your group's page.
  • Read the texts and try to identify arguments about the use of Pandemrix. Note that arguments can be (and most are) indirect arguments.
  • Rewrite the arguments in such a way that they can be understood outside the original context.
  • Place the arguments into a hierarchical tree of attacking and defending arguments pointing toward the main statement about Pandemrix use.
  • You can also make up your own arguments, or if you have extra time, read additional material (see end of the page).
  • When each group has done their own part, there will be a general discussion about all argumentations by the groups. All argumentations will be merged onto this page based on the discussion.
  • Think: How many readers do you need to make this extra effort of collecting, organising and synthesising information and opinions a worthwhile activity of social learning?

Pandemrix should not be used because of narcolepsy risk

How to read discussions

Statements: Pandemrix should not be used any more anywhere because its narcolepsy risk is too high.

Resolution: Resolution not yet found.

(A stable resolution, when found, should be updated to the main page.)

Argumentation:

⇤B10 : All data compiled to date indicate that pandemic vaccines including Pandemrix match the excellent safety profile of seasonal influenza vaccines, which have been used for more than 60 years. --Oluyemitoyinbo 11:12, 1 April 2011 (EEST)

⇤B11 : Adjuvanted vaccines commonly provide a stronger immune response than unadjuvanted vaccines and also provide a broader immune response allowing for some potential drift of the influenza virus (Pandemrix is an adjuvanted vaccine). --Oluyemitoyinbo 11:12, 1 April 2011 (EEST)

⇤B12 : The number of cases of side effects of H1N1 vaccines (including Pandemrix) is in line with normal background rates on a population basis, as reported in a recent study European Medicines Agency --Oluyemitoyinbo 11:12, 1 April 2011 (EEST)

⇤A1 : According to EMA, data received so far is still insufficient to establish a causal relationship between Pandemrix and narcolepsy. One possible explanation for the results is that Pandemrix could interact with unknown local environmental and/or genetic factor in contributing to the increased risk of narcolepsy among the vaccinated population aged 4 to 19 years in Finland --Jacob Attipoe 11:18, 1 April 2011 (EEST)

⇤A2 : The overall annual incidence of narcolepsy remained consistent with prevaccination scenarios --Jacob Attipoe 11:22, 1 April 2011 (EEST)

←A1 Even though a nine fold increase in narcolepsy was found in vaccinated population, the occurrence of narcolepsy was still very rare with this apparent increase. A number of different reasons may account for the observed rise in the incidence of narcolepsy namely: A (H1N1) infection, vaccination, combined effect of infection and vaccination, or some other factor entirely. Infections have been documented as causing narcolepsy. --Jacob Attipoe 11:18, 1 April 2011 (EEST)

⇤A1 : No similar increase in incidence of narcolepsy is reported in other Nordic countries. Canada has extensively used this type of vaccine with no evidence of increased risk for narcolepsy --Jacob Attipoe 11:18, 1 April 2011 (EEST)

←A2 : as there is presently no swine flu epidemic in Finland, there is no immediate need for swine flu vaccination --Jacob Attipoe 11:18, 1 April 2011 (EEST)


⇤1 : Despite risks, Pandemrix is an effective vaccine and has clearly net positive effects in countries where emergency treatment is poorly available for severe swine flu cases. --Jouni 23:05, 31 March 2011 (EEST)

←2 : The reputation of Pandemrix is globally so poor that it is impossible to use it any more. --Jouni 23:05, 31 March 2011 (EEST)

←3 In Finland, THL decided to stop the use of Pandemrix. --Jouni 23:05, 31 March 2011 (EEST), [1]
⇤E6 : The vaccination used last year will most likely protect also against the possible swine flu epidemic of this year, although the virus has changed a bit. --Sallamari Tynkkynen 10:57, 1 April 2011 (EEST) [2]
←E7 : Vaccination is a very good method of preventing swine flu infections. --Sallamari Tynkkynen 10:59, 1 April 2011 (EEST) [3]
←E8 : WHO recommended that H1N1 virus strain be included in the seasonal flu vaccines for the 2009/2010 season, because H1N1 is still in circulation, but behaving like a seasonal flu virus. --Anna Kokkonen 11:10, 1 April 2011 (EEST) [4]
←E9 : The information supplied on the safety and effectiveness of three of the pandemic-influenza vaccines was considered complete enough for the Agency's Committee for Medicinal Products for Human Use to recommend their use outside a pandemic situation. --Anna Kokkonen 11:10, 1 April 2011 (EEST) [5]

⇤E4 : The side effects of Pandemrix have been accentuated, although the benefits are much more significant. --Sallamari Tynkkynen 10:50, 1 April 2011 (EEST) [6]

⇤E5 : Nursing staff in hospitals should be vaccinated; it is their responsibility as medical professionals. --Sallamari Tynkkynen 10:54, 1 April 2011 (EEST) [7]

--D1 : The decision to use Pandemrix was probably led by panic and other choices should be considered at this point --Carmen Gil 11:25, 1 April 2011 (EEST)

←D2 : Finland used a vaccination with additives, against the recommendation of WHO --Carmen Gil 11:25, 1 April 2011 (EEST)
←D3 : Additives can cause flu-like symptoms, increasing the public's opinion against vaccination --Carmen Gil 11:25, 1 April 2011 (EEST)

⇤D4 : Pandemrix has a lower Hg content than other vaccines (2.5 vs 25 µg), which could cause other neurological problems in children --Carmen Gil 11:25, 1 April 2011 (EEST)


Discussion groups:


Additional material:

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