Publications of the risk research group, KTL (YTOS)

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Publications of the risk research group, KTL (YTOS) is a (hopefully) comprehensible list of published scientific articles and other publications.


Manuscript information is moved here when the material listed in Publishing plan of the risk research group, KTL (YTOS) has been published.


Scientific, peer-reviewed publications

1. in international scientific journals (in English)

Jouni T. Tuomisto, Andrew Wilson, John S. Evans and Marko Tainio. Uncertainty in mortality response to airborne fine particulate matter: Combining European air pollution experts. Reliability Engineering & System Safety 93: 5, 732-744 (May 2008). doi:doi:10.1016/j.ress.2007.03.002 (intranet)

Franc MA, Moffat ID, Boutros PC, Tuomisto JT, Tuomisto J, Pohjanvirta R, Okey AB. Patterns of dioxin-altered mRNA expression in livers of dioxin-sensitive versus dioxin-resistant rats. Arch Toxicol. 2008 May 9.

Leino O, Tainio M, Tuomisto JT. Comparative risk analysis of dioxins in fish and fine particles from heavy-duty vehicles. Risk Anal. 2008 Feb;28(1):127-40.

Cooke RM, Wilson AM, Tuomisto JT, Morales O, Tainio M, Evans JS. A probabilistic characterization of the relationship between fine particulate matter and mortality: elicitation of European experts. Environ Sci Technol. 2007 Sep 15;41(18):6598-605.

Main KM, Kiviranta H, Virtanen HE, Sundqvist E, Tuomisto JT, Tuomisto J, Vartiainen T, Skakkebaek NE, Toppari J. Flame retardants in placenta and breast milk and cryptorchidism in newborn boys. Environ Health Perspect. 2007 Oct;115(10):1519-26.

Tainio M, Tuomisto JT, Hänninen O, Ruuskanen J, Jantunen MJ, Pekkanen J. Parameter and model uncertainty in a life-table model for fine particles (PM2.5): a statistical modeling study. Environ Health. 2007 Aug 23;6:24.

Kiljunen M, Vanhatalo M, Mäntyniemi S, Peltonen H, Kuikka S, Kiviranta H, Parmanne R, Tuomisto JT, Vuorinen PJ, Hallikainen A, Verta M, Pönni J, Jones RI, Karjalainen J. Human dietary intake of organochlorines from Baltic herring: implications of individual fish variability and fisheries management. Ambio. 2007 Apr;36(2-3):257-64.

Niittynen M, Simanainen U, Syrjälä P, Pohjanvirta R, Viluksela M, Tuomisto J, Tuomisto JT. Differences in acute toxicity syndromes of 2,3,7,8-tetrachlorodibenzo-p-dioxin and 1,2,3,4,7,8-hexachlorodibenzo-p-dioxin in rats. Toxicology. 2007 Jun 3;235(1-2):39-51. Epub 2007 Mar 15.

van Bree L, Fudge N, Tuomisto JT, Brunekreef B. Closing the gap between science and policy on air pollution and health. J Toxicol Environ Health A. 2007 Feb 1;70(3-4):377-81.

Tuomisto JT, Tainio M. An economic way of reducing health, environmental, and other pressures of urban traffic: a decision analysis on trip aggregation. BMC Public Health. 2005 Nov 25;5:123.

Tuomisto JT, Pekkanen J. Assessing environmental health risks or net health benefits? Scand J Public Health. 2005;33(3):162-3.

Kiviranta H, Tuomisto JT, Tuomisto J, Tukiainen E, Vartiainen T. Polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls in the general population in Finland. Chemosphere. 2005 Aug;60(7):854-69.

Hänninen OO, Palonen J, Tuomisto JT, Yli-Tuomi T, Seppänen O, Jantunen MJ. Reduction potential of urban PM2.5 mortality risk using modern ventilation systems in buildings. Indoor Air. 2005 Aug;15(4):246-56.

Hänninen OO, Tuomisto JT, Jantunen MJ, Lebret E. Characterization of model error in a simulation of fine particulate matter exposure distributions of the working age population in Helsinki, Finland. J Air Waste Manag Assoc. 2005 Apr;55(4):446-57.

Fletcher N, Giese N, Schmidt C, Stern N, Lind PM, Viluksela M, Tuomisto JT, Tuomisto J, Nau H, Håkansson H. Altered retinoid metabolism in female Long-Evans and Han/Wistar rats following long-term 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-treatment. Toxicol Sci. 2005 Aug;86(2):264-72. Epub 2005 Apr 27.

Tainio M, Tuomisto JT, Hänninen O, Aarnio P, Koistinen KJ, Jantunen MJ, Pekkanen J. Health effects caused by primary fine particulate matter (PM2.5) emitted from buses in the Helsinki metropolitan area, Finland. Risk Anal. 2005 Feb;25(1):151-60.

Tuomisto JT, Tuomisto J, Tainio M, Niittynen M, Verkasalo P, Vartiainen T, Kiviranta H, Pekkanen J. Risk-benefit analysis of eating farmed salmon. Science. 2004 Jul 23;305(5683):476-7; author reply 476-7.

Simanainen U, Adamsson A, Tuomisto JT, Miettinen HM, Toppari J, Tuomisto J, Viluksela M. Adult 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure and effects on male reproductive organs in three differentially TCDD-susceptible rat lines. Toxicol Sci. 2004 Oct;81(2):401-7. Epub 2004 Jul 7.

Miettinen HM, Huuskonen H, Partanen AM, Miettinen P, Tuomisto JT, Pohjanvirta R, Tuomisto J. Effects of epidermal growth factor receptor deficiency and 2,3,7,8-tetrachlorodibenzo-p-dioxin on fetal development in mice. Toxicol Lett. 2004 May 2;150(3):285-91.

Simanainen U, Haavisto T, Tuomisto JT, Paranko J, Toppari J, Tuomisto J, Peterson RE, Viluksela M. Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines. Toxicol Sci. 2004 Jul;80(1):101-8. Epub 2004 Apr 14.

Simanainen U, Tuomisto JT, Pohjanvirta R, Syrjälä P, Tuomisto J, Viluksela M. Postnatal development of resistance to short-term high-dose toxic effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in TCDD-resistant and -semiresistant rats. Toxicol Appl Pharmacol. 2004 Apr 1;196(1):11-9.

Tuomisto JT, Pekkanen J, Kiviranta H, Tukiainen E, Vartiainen T, Tuomisto J. Soft-tissue sarcoma and dioxin: A case-control study. Int J Cancer. 2004 Mar 1;108(6):893-900.

Simanainen U, Tuomisto JT, Tuomisto J, Viluksela M. Dose-response analysis of short-term effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin in three differentially susceptible rat lines. Toxicol Appl Pharmacol. 2003 Mar 1;187(2):128-36.

Niittynen M, Tuomisto JT, Auriola S, Pohjanvirta R, Syrjälä P, Simanainen U, Viluksela M, Tuomisto J. 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced accumulation of biliverdin and hepatic peliosis in rats. Toxicol Sci. 2003 Jan;71(1):112-23.

Kiukkonen A, Viluksela M, Sahlberg C, Alaluusua S, Tuomisto JT, Tuomisto J, Lukinmaa PL. Response of the incisor tooth to 2,3,7,8-tetrachlorodibenzo-p-dioxin in a dioxin-resistant and a dioxin-sensitive rat strain. Toxicol Sci. 2002 Oct;69(2):482-9.

Pohjanvirta R, Korkalainen M, McGuire J, Simanainen U, Juvonen R, Tuomisto JT, Unkila M, Viluksela M, Bergman J, Poellinger L, Tuomisto J. Comparison of acute toxicities of indolo[3,2-b]carbazole (ICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive rats. Food Chem Toxicol. 2002 Jul;40(7):1023-32.

Simanainen U, Tuomisto JT, Tuomisto J, Viluksela M. Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains. Toxicol Appl Pharmacol. 2002 May 15;181(1):38-47.

Levy JI, Carrothers TJ, Tuomisto JT, Hammitt JK, Evans JS. Assessing the public health benefits of reduced ozone concentrations. Environ Health Perspect. 2001 Dec;109(12):1215-26. Review.

Jämsä T, Viluksela M, Tuomisto JT, Tuomisto J, Tuukkanen J. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on bone in two rat strains with different aryl hydrocarbon receptor structures. J Bone Miner Res. 2001 Oct;16(10):1812-20.

Kattainen H, Tuukkanen J, Simanainen U, Tuomisto JT, Kovero O, Lukinmaa PL, Alaluusua S, Tuomisto J, Viluksela M. In utero/lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure impairs molar tooth development in rats. Toxicol Appl Pharmacol. 2001 Aug 1;174(3):216-24.

Viluksela M, Bager Y, Tuomisto JT, Scheu G, Unkila M, Pohjanvirta R, Flodström S, Kosma VM, Mäki-Paakkanen J, Vartiainen T, Klimm C, Schramm KW, Wärngård L, Tuomisto J. Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains. Cancer Res. 2000 Dec 15;60(24):6911-20.

Kiviranta H, Vartiainen T, Verta M, Tuomisto JT, Tuomisto J. High fish-specific dioxin concentrations in Finland. Lancet. 2000 May 27;355(9218):1883-5.

Tuomisto JT, Viluksela M, Pohjanvirta R, Tuomisto J. Changes in food intake and food selection in rats after 2,3,7, 8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. Pharmacol Biochem Behav. 2000 Mar;65(3):381-7.

Viluksela M, Unkila M, Pohjanvirta R, Tuomisto JT, Stahl BU, Rozman KK, Tuomisto J. Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on liver phosphoenolpyruvate carboxykinase (PEPCK) activity, glucose homeostasis and plasma amino acid concentrations in the most TCDD-susceptible and the most TCDD-resistant rat strains. Arch Toxicol. 1999 Aug;73(6):323-36.

Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. TCDD-induced anorexia and wasting syndrome in rats: effects of diet-induced obesity and nutrition. Pharmacol Biochem Behav. 1999 Apr;62(4):735-42.

Pohjanvirta R, Viluksela M, Tuomisto JT, Unkila M, Karasinska J, Franc MA, Holowenko M, Giannone JV, Harper PA, Tuomisto J, Okey AB. Physicochemical differences in the AH receptors of the most TCDD-susceptible and the most TCDD-resistant rat strains. Toxicol Appl Pharmacol. 1999 Feb 15;155(1):82-95.

Tuomisto JT, Viluksela M, Pohjanvirta R, Tuomisto J. The AH receptor and a novel gene determine acute toxic responses to TCDD: segregation of the resistant alleles to different rat lines. Toxicol Appl Pharmacol. 1999 Feb 15;155(1):71-81.

Valjakka A, Vartiainen J, Tuomisto L, Tuomisto JT, Olkkonen H, Airaksinen MM. The fasciculus retroflexus controls the integrity of REM sleep by supporting the generation of hippocampal theta rhythm and rapid eye movements in rats. Brain Res Bull. 1998 Sep 15;47(2):171-84.

Pohjanvirta R, Unkila M, Lindén J, Tuomisto JT, Tuomisto J. Toxic equivalency factors do not predict the acute toxicities of dioxins in rats. Eur J Pharmacol. 1995 Dec 7;293(4):341-53.

Tuomisto JT, Pohjanvirta R, Unkila M, Tuomisto J. 2,3,7,8-Tetrachlorodibenzo-p-dioxin-induced anorexia and wasting syndrome in rats: aggravation after ventromedial hypothalamic lesion. Eur J Pharmacol. 1995 Dec 7;293(4):309-17.

Unkila M, Pohjanvirta R, Tuomisto JT, Tuomisto J. Alterations in plasma tryptophan binding to albumin in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated Long-Evans rats. Eur J Pharmacol. 1995 Jul 1;293(2):115-21.

Vartiainen T, Lampi P, Tuomisto JT, Tuomisto J. Polychlorodibenzo-p-dioxin and polychlorodibenzofuran concentrations in human fat samples in a village after pollution of drinking water with chlorophenols. Chemosphere. 1995 Apr;30(8):1429-38.

Unkila M, Ruotsalainen M, Pohjanvirta R, Viluksela M, MacDonald E, Tuomisto JT, Rozman K, Tuomisto J. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on tryptophan and glucose homeostasis in the most TCDD-susceptible and the most TCDD-resistant species, guinea pigs and hamsters. Arch Toxicol. 1995;69(10):677-83.

Unkila M, Pohjanvirta R, MacDonald E, Tuomisto JT, Tuomisto J. Dose response and time course of alterations in tryptophan metabolism by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the most TCDD-susceptible and the most TCDD-resistant rat strain: relationship with TCDD lethality. Toxicol Appl Pharmacol. 1994 Oct;128(2):280-92.

Unkila M, Tuomisto JT, Pohjanvirta R, MacDonald E, Tuomisto L, Koulu M, Tuomisto J. Effect of a single lethal dose of TCDD on the levels of monoamines, their metabolites and tryptophan in discrete brain nuclei and peripheral tissues of Long-Evans rats. Pharmacol Toxicol. 1993 Apr-May;72(4-5):279-85.

Pohjanvirta R, Unkila M, Tuomisto JT, Vuolteenaho O, Leppäluoto J, Tuomisto J. Effect of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on plasma and tissue beta-endorphin-like immunoreactivity in the most TCDD-susceptible and the most TCDD-resistant rat strain. Life Sci. 1993;53(19):1479-87.

Tuomisto JT, Unkila M, Pohjanvirta R, Koulu M, Tuomisto L. Effect of a single dose of TCDD on the level of histamine in discrete nuclei in rat brain. Agents Actions. 1991 May;33(1-2):154-6.

2. in international scientific journals (in other languages)

3. in international proceedings

4. in Finnish scientific journals or proceedings

Scientific, non-peer-reviewed publications

1. meeting abstracts, posters, and oral presentations

2. books, book chapters, reports, and monographs

  • Tuomisto JT: Ilmansaasteet. (Farmakologia ja toksikologia, Medicina, Kuopio, 2008) in Finnish

3. doctoral and other thesis

4. other

Non-scientific publications

1. books

2. articles in non-scientific journals

3. audiovisual products (own products)

4. interviews or news in newspapers or other media