Difference between revisions of "Thyroid disorders"
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| Leese, G. P. Flynn, R. V., Jung, R. T.; MacDonald, T. M.; Murphy, M. J; Morris, A. D. Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS). Clinical Endocrinology. 68(2):311-316, February 2008. | | Leese, G. P. Flynn, R. V., Jung, R. T.; MacDonald, T. M.; Murphy, M. J; Morris, A. D. Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS). Clinical Endocrinology. 68(2):311-316, February 2008. | ||
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Revision as of 11:48, 29 June 2010
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Scope
What is the prevalence of ENDPOINT in the general population?
Definition
Studies mainly focused on iodine deficiency not included.
| 21/1000 PHPT prevalence was found in women aged 55-75 years, which is equivalent to 3/1000 prevalence in the general population. | Primary hyperparathyroidism (PHPT) | Characterised by mild hypercalcaemia and few traditional classic (bone and kidney) manifestations. | Adami S, Marcocci C, Gatti D. Epidemiology of primary hyperparathyroidism in Europe. J Bone Miner Res. 2002 Nov;17 Suppl 2:N18-23. |
| 68yrs | |||
| 13.5% with abnormal TSH levels. | |||
| In Jutland, it was mainly thyroid hyperfunction (9.7% had low, 3.8% had high serum TSH), | |||
| In Iceland, it was impaired thyroid function (1% had low, 18% had high serum TSH). | Iceland n=100, Jutland (Denmark) n=423, abnormal thyroid function | Serum TSH level outside reference range | Peter Laurberg, Klaus M. Pedersen, Astradur Hreidarsson, Nikulas Sigfusson, Eigil Iversen and Preben R. Knudsen. Iodine Intake and the Pattern of Thyroid Disorders: A Comparative Epidemiological Study of Thyroid Abnormalities in the Elderly in Iceland and in Jutland, Denmark. The Journal of Clinical Endocrinology & Metabolism 1998 Vol. 83, No. 3 765-769. |
| Overall prevalence of thyroid dysfunction has increased from 2.3% to 3.8% (1994-2001). | |||
| The prevalence of ever having had hyperthyroidism increased from 0.86% to 1.26% in females and 0.17% to 0.24% in males. | |||
| The standardized incidence of hyperthyroidism increased from 0.68 to 0.87 per 1000 females/year, representing a 6.3% annual increase. | |||
| The prevalence of primary hypothyroidism increased from 3.12% to 5.14% in females and 0.51% to 0.88% in males. | |||
| The standardized incidence of primary hypothyroidism did not change and varied between 3.90 and 4.89 per 1000 females/year. | |||
| Incidence of hypothyroidism in males increased from 0.65 to 1.01 per 1000 males/year. | Tayside (Scotland), 1994-2001, thyroid dysfunction, | Leese, G. P. Flynn, R. V., Jung, R. T.; MacDonald, T. M.; Murphy, M. J; Morris, A. D. Increasing prevalence and incidence of thyroid disease in Tayside, Scotland: the Thyroid Epidemiology Audit and Research Study (TEARS). Clinical Endocrinology. 68(2):311-316, February 2008. |
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