Developmental toxicity

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Developmental toxicity: toxic effects occurring during the developing period, especially during embryonal stages of development. This period is often very sensitive to many chemicals, and the effect may range from reversible effects to embryonal or foetal death. Teratogenicity is one form of developmental toxicity, where a chemical causes permanent malformations. PCDD/Fs cause embryonal or foetal death at high exposures, teratogenicity such as cleft palate in some animal species, and they have been implied of being endocrine disrupters (see this). [1]


  1. Jouko Tuomisto, Terttu Vartiainen and Jouni T. Tuomisto: Dioxin synopsis. Report. National Institute for Health and Welfare (THL), ISSN 1798-0089 ; 14/2011 [1]