Difference between revisions of "Dioxin concentrations during a lifetime of an average Finn"

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{{Dioxin PBPK model
 
{{Dioxin PBPK model
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|peakend=20000
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|dosepic=0.0000069
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|peakdose=0.0000069
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|dosebase1=0.0000069
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|dose1=0.0000069
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|dosebase2=0.0000069
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|dose2=0.0000069
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|dosebase3=0.0000069
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|dose3=0.0000069
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|dosebase5=0.0000069
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|dose5=0.0000069
 
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Revision as of 19:56, 4 January 2008

Scope

Dioxin concentrations during a lifetime of an average Finn describes the development of dioxin concentrations in several tissues in an average Finnish woman exposed to current (2008) levels.

Definition

Data

List of data files or sources:

The data is based on author judgement

  • Start of pic (days) 100
  • End of pic (days) 20000
  • Dose of pic (ng/min) 0.0000069
  • Dose of base 1 (ng/min) 0.0000069
  • Dose of base 2 (ng/min) 0.0000069
  • Dose of base 3 (ng/min) 0.0000069
  • Dose of base 4 (ng/min) 0.0000069
  • Dose of base 5 (ng/min) 0.0000069

Causality

List of parents:

  • None

Formula

Dioxin PBPK model
The results are total amounts (ng) of dioxin, except blood concentration (ng/l).

See the model documentation

The input data used for this variable:
  • Intake at age 0 - 5 a (ng/min) 0.0000069
  • Intake at age 5 - 10 a (ng/min) 0.0000069
  • Intake at age 10-15 a (ng/min) 0.0000069
  • Intake at age 15 - 40 a (ng/min) 0.0000069
  • Intake at age 40 - a (ng/min) 0.0000069
  • Start of peak intake (days) 100
  • End of peak intake (days) 20000
  • Additional peak intake (ng/min) 0.0000069

Click here to run the model

Unit

ng/kg fat (blood) or ng (other organs)

Result

For the full result, run the model again.

time (min) Concentration in blood Quantity in fat Quantity in visceral organs Quantity in muscle and skin Quantity in liver
10,000 0,000 0,000 0,000 0,000 0,000
1 000 010,000 0,027 10,863 0,781 0,750 0,395
2 000 010,000 0,035 23,469 1,206 1,272 0,598
3 000 010,000 0,039 36,141 1,550 1,837 0,760
4 000 010,000 0,041 48,702 1,863 2,538 0,913
5 000 010,000 0,043 61,103 2,141 3,419 1,070
6 000 010,000 0,035 75,254 1,882 3,328 0,980
7 000 010,000 0,029 89,400 1,660 3,186 0,919
8 000 010,000 0,026 103,273 1,559 3,133 0,923
9 000 010,000 0,028 116,203 1,705 3,620 1,075
10 000 000,000 0,030 129,311 1,833 3,948 1,215
11 000 000,000 0,032 142,528 1,947 4,188 1,336
12 000 000,000 0,034 155,811 2,051 4,381 1,438
13 000 000,000 0,035 169,138 2,147 4,548 1,524
14 000 000,000 0,037 182,495 2,235 4,696 1,598
15 000 000,000 0,038 195,877 2,317 4,829 1,664
16 000 000,000 0,039 209,279 2,394 4,948 1,722
17 000 000,000 0,040 222,698 2,466 5,056 1,776
18 000 000,000 0,042 236,132 2,534 5,152 1,826
19 000 000,000 0,043 249,579 2,597 5,238 1,873
20 000 000,000 0,044 263,038 2,657 5,315 1,916
21 000 000,000 0,045 276,508 2,714 5,384 1,957
22 000 000,000 0,045 289,988 2,768 5,444 1,996
23 000 000,000 0,046 303,477 2,819 5,498 2,033
24 000 000,000 0,047 316,974 2,867 5,544 2,068
25 000 000,000 0,048 330,478 2,913 5,585 2,101
26 000 000,000 0,049 343,989 2,956 5,619 2,132
27 000 000,000 0,049 357,507 2,998 5,649 2,162
28 000 000,000 0,050 371,030 3,038 5,673 2,191
29 000 000,000 0,050 383,221 3,064 5,672 2,210
30 000 000,000 0,050 390,042 3,048 5,591 2,198
31 000 000,000 0,050 396,861 3,033 5,513 2,187
32 000 000,000 0,050 403,679 3,018 5,436 2,177
33 000 000,000 0,049 410,495 3,004 5,361 2,166
34 000 000,000 0,049 417,309 2,991 5,288 2,157
35 000 000,000 0,049 424,121 2,978 5,216 2,147
36 000 000,000 0,049 430,933 2,965 5,145 2,139
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