ERF of fish intake on neurological disorders in adults
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Contents
Scope
What is the exposure-response function (ERF) of omega-3-rich fish intake on neurological disorders in adults? Especially the focus is on brain infarction.
Definition
Data
In a recent study, 3660 over 65-year-old individuals were monitored for five years, and the change in small brain infarctions was observed by magnetic resonance imageing. The infaction risk was 25 % lower in those who ate at least three portions of omega-3-rich fish meals per week, and 13 % lower in those who ate one meal per week.[1]
Causality
None identified.
Unit
% change / # fish portions per week
Formula
Result
| Obs | Disease | Response metric | Exposure route | Exposure metric | Exposure unit | Threshold | ERF parameter | ERF | Description |
|---|---|---|---|---|---|---|---|---|---|
| 1 | Subclinical brain infarct (one or more) | Prevalence | Ingestion | Intake of tuna/other fish | ≥3 times/week vs. <1/month | RR | 0.74(0.54-1.01) | Virtanen et al. 2008 | |
| 2 | Any prevalent subclinical brain infarct | Prevalence | Ingestion | Intake of tuna/other fish | Each one serving per week | Decrease in RR % | 7(0.6-12) | Virtanen et al. 2008 | |
| 3 | Subclinical brain infarct (one or more) | Incidence | Ingestion | Intake of tuna/other fish | ≥3 times/week vs. <1/month | RR | 0.56(0.30-1.07) | Virtanen et al. 2008 | |
| 4 | Any incident subclinical brain infarct | Incidence | Ingestion | Intake of tuna/other fish | Each one serving per week | Decrease in RR % | 11(0.7-22) | Virtanen et al. 2008 |
See also
References
- ↑ Fish consumption and risk of subclinical brain abnormalities on MRI in older adults Jyrki K. Virtanen, David S. Siscovick, Will T. Longstreth, Lewis H. Kuller, Dariush Mozaffarian Neurology 2008;71:439–446.
