ERF of heavy metals on selected endpoints
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Contents
Scope
What are the exposure-response functions of arsenic (As), nickel (Ni), mercury (Hg), lead (Pb), chromium (Cr), cadmium (Cd) for the relevant health endpoints of each metal?
Definition
Data
ID | Use | Popolation group | Pollutant | Expoure route | Exposure time [years] | Effect | Absolute risk | Exposure unit respectively intake rate | YLL | YLD | IQ points lost |
Functions recommended for usage | |||||||||||
1 | 1 | All | As | Ingestion | 70 | Skin cancer | 0.00002 | ug/day | 6.09 | 0.19 | 0 |
2 | 1 | All | As | Inhalation | 70 | Skin cancer | 0.0004 | ug/m3 | 6.09 | 0.19 | 0 |
3 | 1 | All | As | Inhalation | 70 | Lung cancer | 0.0015 | ug/m3 | 15.95 | 0.26 | 0 |
4 | 1 | All | As | Ingestion | 70 | Bladder cancer | 0.0001 | ug/day | 4.63 | 0.36 | 0 |
5 | 1 | All | As | Inhalation | 70 | Bladder cancer | 0.000004 | ug/m3 | 4.63 | 0.36 | 0 |
8 | 1 | All | As | Ingestion | 1 | Still birth | 0.0001044 | ug/day | 0.00 | 1.28 | 0 |
9 | 1 | All | As | Inhalation | 1 | Still birth | 0.002088 | ug/m3 | 0.00 | 1.28 | 0 |
17 | 1 | Minors | Pb | Inhalation | 5 | Children's IQ | 0.1 | ug/m3 | 0.00 | 0.00 | 1 |
23 | 1 | All | Hg | Inhalation | 35 | CHS effects in adults - ataxia | 0.00014 | ug/m3 | 0.01 | 0.12 | 0 |
25 | 1 | All | Ni | Inhalation | 70 | Lung cancer | 0.00038 | ug/m3 | 15.95 | 0.26 | 0 |
103 | 1 | All | Cd | Inhalation | 70 | Cancer 85% fatal | 0.0018 | ug/m3 | 15.95 | 0.26 | 0 |
104 | 1 | All | CrVI | Inhalation | 70 | Cancer 85% fatal | 0.012 | ug/m3 | 15.95 | 0.26 | 0 |
106 | 1 | All | PCBs | Inhalation | 70 | Cancer 50% fatal | 0.0001 | ug/m3 | 9.38 | 0.15 | 0 |
107 | 1 | Age<1 | Pb | Ingestion | 1 | Children's IQ | 0.042 | ug/day | 0.00 | 0.00 | 1 |
Functions used for sensitivity analysis | |||||||||||
6 | 2 | All | As | Ingestion | 35 | Cardiovascular mortality | 0.003 | ug/day | 12.80 | 0.00 | 0 |
7 | 2 | All | As | Inhalation | 35 | Cardiovascular mortality | 0.02 | ug/m3 | 12.80 | 0.00 | 0 |
10 | 2 | All | Cd | Ingestion | 35 | Osteoporosis | 0.008 | ug/day | 0.00 | 0.28 | 0 |
11 | 2 | All | Cd | Inhalation | 35 | Osteoporosis | 0.16 | ug/m3 | 0.00 | 0.28 | 0 |
12 | 2 | All | Cd | Ingestion | 35 | Renal dysfunction | 0.0004 | ug/day | 0.00 | 0.64 | 0 |
13 | 2 | All | Cd | Inhalation | 35 | Renal dysfunction | 0.008 | ug/m3 | 0.00 | 0.64 | 0 |
18 | 2 | All | Pb | Food | 1 | Anaemia | 0.000048 | ug/day | 0.00 | 0.64 | 0 |
19 | 2 | All | Pb | Water | 1 | Anaemia | 0.0002 | ug/l | 0.00 | 0.64 | 0 |
20 | 2 | All | Pb | Inhalation | 1 | Anaemia | 0.0013 | ug/m3 | 0.00 | 0.64 | 0 |
24 | 2 | All | Hg | Inhalation | 35 | Renal dysfunction - preclinical effects | 0.002 | ug/m3 | 0.06 | 0.58 | 0 |
Functions not used in ESPREME/DROPS | |||||||||||
14 | 3 | All | CrVI | Inhalation | 70 | Lung cancer | 0.004 | ug/m3 | 15.95 | 0.26 | 0 |
15 | 3 | Minors | Pb | Food | 5 | Children's IQ | 0.32 | ug/day | 0.00 | 0.00 | 1 |
16 | 3 | Minors | Pb | Water | 5 | Children's IQ | 0.48 | ug/l | 0.00 | 0.00 | 1 |
101 | 3 | All | Cd | Inhalation | 70 | Lung cancer | 0.0018 | ug/m3 | 15.95 | 0.26 | 0 |
102 | 3 | All | As | Inhalation | 70 | Cancer 85% fatal | 0.0043 | ug/m3 | 15.95 | 0.26 | 0 |
105 | 3 | All | Ni | Inhalation | 70 | Cancer 85% fatal | 0.00024 | ug/m3 | 15.95 | 0.26 | 0 |
21 | 2/3 | Minors | Hg | Ingestion | 1 | Children's IQ | 0.149 | ug/day | 0.00 | 0.00 | 1 |
22 | 2/3 | All | Hg | Ingestion | 35 | CHS effects in adults - ataxia | 0.0013 | ug/day | 0.01 | 0.12 | 0 |
Dependencies
None defined.
Unit
Formula
Result
See also
References
- ↑ http://espreme.ier.uni-stuttgart.de/html/ERFs.html ESPREME home page