User:Erkki Kuusisto

Erkki Kuusisto (Researcher)

Contact info

Department of Environmental Health

National Institute for Health and Welfare (THL)

POB 95, FIN-70701 Kuopio, Finland.

Tel. +358-20-61 06 391; mob. +358-40-841 5665

e-mail firstname.lastname@thl.fi

Main topics of research

Health impact analysis of:

• urban road traffic (INTARESE / WP3.1 traffic)
• environmental noise (HEIMTSA / noise case; SETURI)

Erkki Kuusisto

Researcher

National Public Health Institute, Centre for Environmental Health Risk Analysis, POB 95, FIN-70701 Kuopio, Finland.

Email: firstname.lastname@thl.fi

phone: +358 20 610 63xx, fax: +358 20 610 6498

Areas of interest

• integrated modeling tools
• risk analysis for road traffic
• environmental noise
• value judgements and decision-making

Current research

Policy options for reducing the health burden and other costs of urban traffic (INTARESE)

Education

• PhD (Neurosciences), University of Kuopio, Finland
• MSc (Cell Biology), University of Jyväskylä, Finland
• MSc (Engineering Physics), Tampere University of Technology, Finland

Selected publications

• E. Kuusisto , T. Kauppinen, I. Alafuzoff: Use of p62 / SQSTM1 antibodies for neuropathological diagnosis. Neuropathol. Appl. Neurobiol. (in press).
• A.J. Tervo, T. Suuronen, S. Kyrylenko, E. Kuusisto, P.H. Kiviranta, A. Salminen, J. Leppänen, A. Poso: Discovering Inhibitors of Human Sirtuin Type 2: Novel Structural Scaffolds. J. Med. Chem. 49, 7239-7241 (2006).
• E. Kuusisto , L. Parkkinen, I. Alafuzoff: Morphogenesis of Lewy bodies: dissimilar incorporation of alpha-synuclein, ubiquitin, and p62. J. Neuropathol. Exp. Neurol. 62, 1241-53 (2003).
• E. Kuusisto , A. Salminen, I. Alafuzoff: Early accumulation of p62 in neurofibrillary tangles in Alzheimer's disease: possible role in tangle formation. Neuropathol. Appl. Neurobiol. 28, 228-237 (2002).
• E. Kuusisto , A. Salminen, I. Alafuzoff: Ubiquitin-binding protein p62 is present in neuronal and glial inclusions in human tauopathies and synucleinopathies. NeuroReport 12, 2085-2090 (2001).
• E. Kuusisto , T. Suuronen, A. Salminen: Ubiquitin-binding protein p62 expression is induced during apoptosis and proteasomal inhibition in neuronal cells. Biochem. Biophys. Res. Commun. 280, 223-228 (2001).
• M. Roschier, E. Kuusisto, T. Suuronen, P. Korhonen, S. Kyrylenko, A. Salminen: Insulin-like growth factor binding protein 5 and type-1 insulin-like growth factor receptor are differentially regulated during apoptosis in cerebellar granule cells. J. Neurochem. 76, 1-11 (2001).
• M. Roschier, E. Kuusisto, A. Salminen: A differential display protocol to identify differentially expressed mRNAs in potassium-deprived cerebellar granule cells. Brain Res. Brain Res. Protoc. 5, 121-131 (2000).
• M. Valden, J. Aaltonen, E. Kuusisto, M. Pessa, C. J. Barnes: 1994. Molecular beam studies of CO oxidation and CO-NO reactions on a supported Pd catalyst. Surf. Sci. 307-309, 193-198 (1994).
• K. Imai, E. Kuusisto, J. Lilja, M. Pessa, D. Suzuki, H. Ozaki, K. Kumazaki: Electrical characterization of Li-doped ZnSe grown by molecular beam epitaxy. J. Crystal Growth 117, 406-409 (1992).

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