Difference between revisions of "INTERA: Di-methyl fumarate in consumer products"
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== References == | == References == | ||
+ | Fraga A, Silva R, Filipe P, Scharrer K, Da Costa J.B, Nußbaum P and Gomes M.M (2010). Allergic contact dermatitis to dimethyl fumarate in footwear. Contact Dermatitis 2010: 62: 121–123 | ||
− | + | Gimenez-Arnau A, Silvestre J.F, Mercader P, De La Cuadra J, Ballester I, Gallardo F, Pujol, R.M, Zimerson E and Bruze M. (2009). Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure. Contact Dermatitis 2009: 61: 249–260 | |
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− | + | Hasan T, Zimerson E. and Bruze M (2010), Persistent Shoe Dermatitis Caused by Dimethyl Fumarate. Acta Dermato-Venereologica 2010: 90: 553-554 | |
+ | |||
+ | Retho C, Accessed 1st March 2011. Analysis of dimethylfumarate. European Commission meeting on 16 June 2009. http://ec.europa.eu/consumers/safety/projects/index_en.htm#dmf | ||
+ | |||
+ | Rantanen T, (2008)The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer. British Journal of Dermatology 2008 159, pp218–221 | ||
+ | |||
+ | RAPEX, advanced 18-04-2011, European Commission, http://ec.europa.eu/consumers/dyna/rapex/rapex_archives_en.cfm | ||
== Related files == | == Related files == |
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Contents
Scope
Di-methyl fumarate concentrations in consumer products that are sold in Europe.
Definition
Data
According to the Hong Kong Trade Development Council (HKTDC) shoes, sofas and chair account for more than 90% of the total DMF products entered in EU (Hong Kong Trade Development Council, 2009). Other consumer products include toys and helmets (reported in the RAPEX database). A case of occupational exposure after contact with working trousers has also been reported (Foti et al. 2009).
The European RAPEX database (RAPEX 2011) provided 185 results (2005-2011) of products which were contaminated with DMF (Table 1).
Dependencies
Unit
mg/kg, ppm or μg/cm2.
Formula
Result
Reference | Country of purchase | Product | Concentration |
RAPEX 2011 | Denmark | Shoes | > 0.1 mg/kg |
RAPEX 2010 | Estonia, Hungary, Poland, Italy, Finland, Germany, Slovakia, France, Bulgaria, Spain, Sweden |
Shoes (N = 59) Jeans (N = 3) Children’s hat (N = 1) |
0.14 - 5409 mg/kg 0.2 - 0,5 mg/kg 1,7 mg/kg |
RAPEX 2009 | Hungary, Italy, Spain, Germany, Portugal, Estonia, Bulgaria, Holland, Greece, Cyprus, Poland, Finland, France, Sweden | Shoes (N = 109 | 0.11 - 2749 mg/kg |
RAPEX 2008 | Sweden, Poland, France | Shoes (N = 3) |
19 mg/kg |
Table 2. Concentrations at the time of purchase
Reference | Country of purchase | Product | Concentration |
Gimenez-Arnou, 2009 | Spain |
Shoes (n=9 Shoes (n=2) |
3-95 ppm 10 & 46 μg/cm2 |
Fraga et al. 2009 | Portugal |
Red boot Black boots |
1.3-11 ppm 120-640 ppm |
Hassan et al. 2010 | Sweden | Shoes | 0.22-2.8 ppm |
Retho et al. 2009 | France |
Slippers (n=52) Sofa |
0.18-610 ppm 0.5 ppm |
Rantanen et al. 2008 | Finland | Chair | 41-400 ppm |
See also
Links to relevant information that does not belong to Definition.
Keywords
References
Fraga A, Silva R, Filipe P, Scharrer K, Da Costa J.B, Nußbaum P and Gomes M.M (2010). Allergic contact dermatitis to dimethyl fumarate in footwear. Contact Dermatitis 2010: 62: 121–123
Gimenez-Arnau A, Silvestre J.F, Mercader P, De La Cuadra J, Ballester I, Gallardo F, Pujol, R.M, Zimerson E and Bruze M. (2009). Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure. Contact Dermatitis 2009: 61: 249–260
Hasan T, Zimerson E. and Bruze M (2010), Persistent Shoe Dermatitis Caused by Dimethyl Fumarate. Acta Dermato-Venereologica 2010: 90: 553-554
Retho C, Accessed 1st March 2011. Analysis of dimethylfumarate. European Commission meeting on 16 June 2009. http://ec.europa.eu/consumers/safety/projects/index_en.htm#dmf
Rantanen T, (2008)The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer. British Journal of Dermatology 2008 159, pp218–221
RAPEX, advanced 18-04-2011, European Commission, http://ec.europa.eu/consumers/dyna/rapex/rapex_archives_en.cfm
Related files
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