Difference between revisions of "INTERA: Di-methyl fumarate in consumer products"

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=== Unit  ===
 
=== Unit  ===
  
mg/kg, ppm or μg/cm'''<sup>2</sup>.'''
+
mg/kg
  
 
=== Formula  ===
 
=== Formula  ===
  
 
== Result  ==
 
== Result  ==
 
<t2b index="Country,Product,Exposure type,Statistical parameter,Ref,Unit" unit="mg/kg, ppm, ug/cm^2" obs="Result">
 
Denmark|Shoes |Before exposure|Single value|1|mg/kg|> 0.1
 
Estonia, Hungary, Poland, Italy, Finland, Germany, Slovakia, France, Bulgaria, Spain, Sweden|Shoes|Before exposure|Min|2|mg/kg|0.14
 
Estonia, Hungary, Poland, Italy, Finland, Germany, Slovakia, France, Bulgaria, Spain, Sweden|Shoes|Before exposure|Max|2|mg/kg|5409
 
Estonia, Hungary, Poland, Italy, Finland, Germany, Slovakia, France, Bulgaria, Spain, Sweden|Jeans|Before exposure|Min|2|mg/kg|0.2
 
Estonia, Hungary, Poland, Italy, Finland, Germany, Slovakia, France, Bulgaria, Spain, Sweden|Jeans|Before exposure|Max|2|mg/kg|0.5
 
Estonia, Hungary, Poland, Italy, Finland, Germany, Slovakia, France, Bulgaria, Spain, Sweden|Children’s hat |Before exposure|Single value|2|mg/kg|1.7
 
Hungary, Italy, Spain, Germany, Portugal, Estonia, Bulgaria, Holland, Greece, Cyprus, Poland, Finland, France, Sweden|Shoes|Before exposure|Min|3|mg/kg|0.11
 
Hungary, Italy, Spain, Germany, Portugal, Estonia, Bulgaria, Holland, Greece, Cyprus, Poland, Finland, France, Sweden|Shoes|Before exposure|Max|3|mg/kg|2749
 
Sweden, Poland, France|Shoes|Before exposure|Unspecified|4|mg/kg|19
 
Spain|Shoes|After exposure|Min|5|ppm|3
 
Spain|Shoes|After exposure|Max|5|ppm|95
 
Spain|Shoes|After exposure|Min|5| ug/cm2|10
 
Spain|Shoes|After exposure|Max|5| ug/cm2|46
 
Portugal|Red boots|After exposure|Min|6|ppm|1.3
 
Portugal|Red boots|After exposure|Max|6|ppm|11
 
Portugal|Black boots|After exposure|Min|6|ppm|120
 
Portugal|Black boots|After exposure|Max|6|ppm|640
 
Sweden|Shoes|After exposure|Min|7|ppm|0.22
 
Sweden|Shoes|After exposure|Max|7|ppm|2.8
 
France|Slippers|After exposure|Min|8|ppm|0.18
 
France|Slippers|After exposure|Max|8|ppm|610
 
France|Sofa|After exposure|Single value|8|ppm|0.5
 
Finland|Chair|After exposure|Min|9|ppm|41
 
Finland|Chair|After exposure|Max|9|ppm|400
 
</t2b>
 
  
 
{{resultlink}}
 
{{resultlink}}
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== References ==
 
== References ==
 
+
#Gimenez-Arnau A. et al. 2009. Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure, Contact Dermatitis 61:249–260.
#RAPEX, advanced 18-04-2011, European Commission, http://ec.europa.eu/consumers/dyna/rapex/rapex_archives_en.cfm
+
#Fraga A. et al. 2010. Allergic contact dermatitis to dimethyl fumarate in footwear, Contact Dermatitis 62:121–123.
#Gimenez-Arnau A, Silvestre J.F, Mercader P, De La Cuadra J, Ballester I, Gallardo F, Pujol, R.M, Zimerson E and Bruze M. (2009). Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure. Contact Dermatitis 2009: 61: 249–260  
+
#Hasan T. et al. 2010. Persistent shoe dermatitis caused by dimethyl fumarate, Acta Dermato-Venereologica 90: 553-554
#Fraga A, Silva R, Filipe P, Scharrer K, Da Costa J.B, Nußbaum P and Gomes M.M (2010). Allergic contact dermatitis to dimethyl fumarate in footwear. Contact Dermatitis 2010: 62: 121–123  
+
#Retho C. Accessed 01-04-2011, Analysis of dimethylfumarate, European Commission meeting on 16 June 2009, http://ec.europa.eu/consumers/safety/projects/index_en.htm#dmf  
#Hasan T, Zimerson E. and Bruze M (2010), Persistent Shoe Dermatitis Caused by Dimethyl Fumarate. Acta Dermato-Venereologica 2010: 90: 553-554
+
#Rantanen T. 2008. The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer, British Journal of Dermatology 159:218–221.
#Retho C, Accessed 1st March 2011. Analysis of dimethylfumarate. European Commission meeting on 16 June 2009. http://ec.europa.eu/consumers/safety/projects/index_en.htm#dmf
+
#ECHA 2010, Annex XV restriction report; proposal for a restriction of dimethyl fumarate, http://echa.europa.eu/doc/restrictions/annex_xv_restriction_report_DMFu_en.pdf
#Rantanen T, (2008)The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer. British Journal of Dermatology 2008 159, pp218–221
+
#Davanzo F. et al. 2009. A case of contact dermatitis to dimethylfumarate in shoes identified in Italy, Annali dell'Istituto Superiore di Sanita 2010, 46:366-369.
  
 
== Related files ==
 
== Related files ==

Latest revision as of 08:57, 16 November 2011


Scope

Di-methyl fumarate concentrations in consumer products that are sold in Europe.

Definition

Data

According to the Hong Kong Trade Development Council (HKTDC) shoes, sofas and chair account for more than 90% of the total DMF products entered in EU (Hong Kong Trade Development Council, 2009). Other consumer products include toys and helmets (reported in the RAPEX database). A case of occupational exposure after contact with working trousers has also been reported (Foti et al. 2009).

The European RAPEX database provided 185 results (2005-2011) of products which were contaminated with DMF. These concentrations are measured just after the products have come to the marked and therefore are refereed as concentrations before exposure. Furthermore, some sutudies were found from the literature, which published measured concentrations from the consumer products after being suspected to cause exposure to DMF. These are referred as concentrations after exposure.

Dependencies

Unit

mg/kg

Formula

Result

Show results


See also

Keywords

References

  1. Gimenez-Arnau A. et al. 2009. Shoe contact dermatitis from dimethyl fumarate: clinical manifestations, patch test results, chemical analysis, and source of exposure, Contact Dermatitis 61:249–260.
  2. Fraga A. et al. 2010. Allergic contact dermatitis to dimethyl fumarate in footwear, Contact Dermatitis 62:121–123.
  3. Hasan T. et al. 2010. Persistent shoe dermatitis caused by dimethyl fumarate, Acta Dermato-Venereologica 90: 553-554
  4. Retho C. Accessed 01-04-2011, Analysis of dimethylfumarate, European Commission meeting on 16 June 2009, http://ec.europa.eu/consumers/safety/projects/index_en.htm#dmf
  5. Rantanen T. 2008. The cause of the Chinese sofa/chair dermatitis epidemic is likely to be contact allergy to dimethylfumarate, a novel potent contact sensitizer, British Journal of Dermatology 159:218–221.
  6. ECHA 2010, Annex XV restriction report; proposal for a restriction of dimethyl fumarate, http://echa.europa.eu/doc/restrictions/annex_xv_restriction_report_DMFu_en.pdf
  7. Davanzo F. et al. 2009. A case of contact dermatitis to dimethylfumarate in shoes identified in Italy, Annali dell'Istituto Superiore di Sanita 2010, 46:366-369.

Related files

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INTERA: Di-methyl fumarate in consumer products. Opasnet . [1]. Accessed 18 Jun 2024.