Difference between revisions of "Benefit-risk assessment of methyl mercury and omega-3 fatty acids in fish"

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(changed according to the newest model)
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{{assessment}}  
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[[Category:Assessments]]
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{{assessment|moderator=Olli}}  
  
  
 
The [[:beneris:Image:Mercury_vs_omega-3_xml.ANA|Analytica model file]] contains the actual calculations for this assessment. The actual code created with the ana-wiki converter can be found from [http://www.pyrkilo.fi/beneris/index.php?title=Risk_assessment_of_MeHg_and_n-3_fatty_acids_in_fish&oldid=3164].  
 
The [[:beneris:Image:Mercury_vs_omega-3_xml.ANA|Analytica model file]] contains the actual calculations for this assessment. The actual code created with the ana-wiki converter can be found from [http://www.pyrkilo.fi/beneris/index.php?title=Risk_assessment_of_MeHg_and_n-3_fatty_acids_in_fish&oldid=3164].  
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This project is planned to serve as a case study to represent the utilization of the [[open assessment]] method.
 +
  
 
== Scope  ==
 
== Scope  ==
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*Population of Finland  
 
*Population of Finland  
 
*Current situation
 
*Current situation
 
<br>
 
  
 
=== Scenarios  ===
 
=== Scenarios  ===
  
This study is a business-as-usual, i.e. a burden-of-disease assessment with only one decision scenario. {{Disclink|Potential scenarios}}  
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* Business as usual (the current situation).
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* A change in total fish intake such that, according to the model, keeps the net effect of fish on the child's IQ positive? {{Disclink|Potential scenarios}}  
  
This project is supposed to serve as a case study to represent the utilization of the pyrkilo method.
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=== Intended users  ===
  
=== Intended users  ===
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* Authorities giving food recommendations.
 +
* Anyone interested.
  
 
=== Participants  ===
 
=== Participants  ===
  
*Beneris researchers
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* [[Beneris]] researchers, especially [[User:Olli|Olli]] and [[User:Patrycja Gradowska|Patrycja Gradowska]].
  
 
== Definition  ==
 
== Definition  ==
 +
 +
[[Image:Benefit-risk assessment of methyl mercury and omega-3 fatty acids in fish diagram.png]]
  
 
=== Decision variables  ===
 
=== Decision variables  ===
  
*None
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* Fish intake of pregnant mothers in Finland [[:beneris:File:Beneris Food consumption pregnant women FINLAND 300507 th.xls|Unpublished data, requires a password]].
  
 
=== Indicators  ===
 
=== Indicators  ===
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'''Environmental variables'''  
 
'''Environmental variables'''  
  
*[[Concentrations of beneficial nutrients in fish|Concentrations of beneficial nutrients in fish]]  
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*[[Concentrations of beneficial nutrients in fish]]  
*[[Mercury and methyl mercury concentrations in fish|Mercury and methyl mercury concentrations in fish]]
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*[[Mercury and methyl mercury concentrations in fish]]
  
 
'''Exposure variables'''  
 
'''Exposure variables'''  
  
*[[Domestic fish consumption of the pregnant women in Finland|Domestic fish consumption of the pregnant women in Finland]]
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*[[Domestic fish consumption of the pregnant women in Finland]]  
*[[Domestic fish consumption of the general population in Finland|Domestic fish consumption of the general population in Finland]]  
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*[[Fish oil intake in Beneris]]  
*[[Fish oil intake in Beneris|Fish oil intake in Beneris]]  
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*[[Methyl mercury intake from fish in Beneris]]
*[[Methyl mercury intake from fish in Beneris|Methyl mercury intake from fish in Beneris]]
 
  
 
'''Population characteristics'''  
 
'''Population characteristics'''  
  
*[[Body weight in Finland|Body weight in Finland]]
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*[[Body weight in Finland]]
  
 
'''Exposure-response functions'''  
 
'''Exposure-response functions'''  
  
*[[ERF of methyl mercury on intelligence quotient|ERF of methyl mercury on intelligence quotient]]  
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*[[ERF of methyl mercury on intelligence quotient]]  
*[[ERF of omega-3 fatty acids on intelligence quotient|ERF of omega-3 fatty acids on intelligence quotient]]
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*[[ERF of omega-3 fatty acids on intelligence quotient]]
  
 
=== Indices  ===
 
=== Indices  ===
  
{| {{prettytable}}
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* Fish (species): Herring, Vendace, Whitefish, Pike, Perch, Salmon, Pike-pearch
|-
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* Water (from which the fish comes from): Baltic Sea, Inland lake
! Fish species
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* '''NOTE!'''
|-
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** Herring is only from the Baltic Sea.
|
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** All pike-pearch is shown as "Inland lake" although a part comes from the Baltic Sea.
*Farmed_salmon(sea+inland)  
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** All salmon is shown as "Inland lake" although most of it comes from the Atlantic Ocean from Norway.
*Wild_salmon(sea)
 
*Herring_(sea)
 
*White_fish(sea)
 
*Sprat(sea)
 
*Perch(sea)
 
*Flounder(sea)
 
*Pike-perch(sea)
 
*Bream(sea)  
 
*Pike(sea)
 
*Vendace(sea)
 
*Burbot(sea)
 
*Wild_salmon(inland)
 
*White_fish(inland)
 
*Perch(inland)
 
*Pike-perch(inland)
 
*Bream(inland)
 
*Pike(inland)
 
*Vendace(inland)
 
*Burbot(inland)
 
 
 
|}
 
 
 
<br>
 
  
 
=== Analyses  ===
 
=== Analyses  ===
  
Interesting population subgroups for exposure might be:
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* What should be done to the total fish intake to keep the net effect of fish on the child's IQ positive?
 
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** For this policy (versus the current situation), what is the [[VOI]] for different [[variable]]s?
*pregnant women with high fish consumption (e.g. 0.95 percentile of fish consumption data of pregnant women)
 
*pregnant women with average fish consumption (e.g. mean fish consumption of pregnant women)
 
*pregnant women with very low or no fish consumption (e.g. 0.05 percentile of fish consumption data of pregnant women)  
 
*general Finnish population with normal fish consumption (as a comparison to the pregnant women scenarios)
 
  
 
== Result  ==
 
== Result  ==
  
 
=== Results  ===
 
=== Results  ===
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 +
[[image:Benefit-risk assessment of methyl mercury and omega-3 fatty acids in fish.png]]
  
 
=== Conclusions  ===
 
=== Conclusions  ===
 
 
[[Category:Risk_assessments]]
 

Revision as of 10:52, 16 September 2009




The Analytica model file contains the actual calculations for this assessment. The actual code created with the ana-wiki converter can be found from [1].

This project is planned to serve as a case study to represent the utilization of the open assessment method.


Scope

Purpose

This assessment evaluates the effects of methyl mercury and omega-3 fatty acids on development of IQ in children. The source of exposure is Finnish fish consumption.

Boundaries

  • Population of Finland
  • Current situation

Scenarios

  • Business as usual (the current situation).
  • A change in total fish intake such that, according to the model, keeps the net effect of fish on the child's IQ positive? D↷

Intended users

  • Authorities giving food recommendations.
  • Anyone interested.

Participants

Definition

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Decision variables

Indicators

Other variables

Environmental variables

Exposure variables

Population characteristics

Exposure-response functions

Indices

  • Fish (species): Herring, Vendace, Whitefish, Pike, Perch, Salmon, Pike-pearch
  • Water (from which the fish comes from): Baltic Sea, Inland lake
  • NOTE!
    • Herring is only from the Baltic Sea.
    • All pike-pearch is shown as "Inland lake" although a part comes from the Baltic Sea.
    • All salmon is shown as "Inland lake" although most of it comes from the Atlantic Ocean from Norway.

Analyses

  • What should be done to the total fish intake to keep the net effect of fish on the child's IQ positive?
    • For this policy (versus the current situation), what is the VOI for different variables?

Result

Results

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Conclusions