Difference between revisions of "Benefit-risk assessment of methyl mercury and omega-3 fatty acids in fish"

From Testiwiki
Jump to: navigation, search
m
Line 1: Line 1:
[[Category:Risk assessments]]
+
The [[:beneris:Image:Mercury_vs_omega-3_xml.ANA|Analytica model file]] contains the actual calculations for this assessment. The actual code created with the ana-wiki converter can be found from [http://www.pyrkilo.fi/beneris/index.php?title=Risk_assessment_of_MeHg_and_n-3_fatty_acids_in_fish&oldid=3164].  
The [[:beneris:Image:Mercury vs omega-3 xml.ANA |Analytica model file]] contains the actual calculations for this assessment.  
 
The actual code created with the ana-wiki converter can be found from [http://www.pyrkilo.fi/beneris/index.php?title=Risk_assessment_of_MeHg_and_n-3_fatty_acids_in_fish&oldid=3164].
 
  
==Scope==
+
== Scope ==
  
===Purpose===
+
=== Purpose ===
  
 
This assessment evaluates the effects of methyl mercury and omega-3 fatty acids on development of IQ in children. The source of exposure is Finnish fish consumption.  
 
This assessment evaluates the effects of methyl mercury and omega-3 fatty acids on development of IQ in children. The source of exposure is Finnish fish consumption.  
  
===Boundaries===
+
=== Boundaries ===
  
* Population of Finland
+
*Population of Finland  
* Current situation
+
*Current situation
  
 +
<br>
  
===Scenarios===
+
=== Scenarios ===
  
This study is a business-as-usual, i.e. a burden-of-disease assessment with only one decision scenario. {{Disclink|Potential scenarios}}
+
This study is a business-as-usual, i.e. a burden-of-disease assessment with only one decision scenario. {{Disclink|Potential scenarios}}  
  
This project is supposed to serve as a case study to represent the utilization of the pyrkilo method.
+
This project is supposed to serve as a case study to represent the utilization of the pyrkilo method.  
  
===Intended users===
+
=== Intended users ===
  
===Participants ===
+
=== Participants ===
  
 
*Beneris researchers
 
*Beneris researchers
  
==Definition==
+
== Definition ==
  
===Decision variables===
+
=== Decision variables ===
  
* None
+
*None
  
===Indicators===
+
=== Indicators ===
  
*[[Intelligence quotient change in children in Beneris]]
+
*[[Intelligence quotient change in children in Beneris|Intelligence quotient change in children in Beneris]]
  
===Other variables===
+
=== Other variables ===
  
'''Environmental variables
+
'''Environmental variables'''
*[[Concentrations of beneficial nutrients in fish]]
 
*[[Mercury and methyl mercury concentrations in fish]]
 
  
'''Exposure variables
+
*[[Concentrations of beneficial nutrients in fish|Concentrations of beneficial nutrients in fish]]  
*[[Domestic fish consumption of the pregnant women in Finland]]
+
*[[Mercury and methyl mercury concentrations in fish|Mercury and methyl mercury concentrations in fish]]
*[[Domestic fish consumption of the general population in Finland]]
 
*[[Fish oil intake in Beneris]]
 
*[[Methyl mercury intake from fish in Beneris]]
 
  
'''Population characteristics
+
'''Exposure variables'''
*[[Body weight in Finland]]
 
  
'''Exposure-response functions
+
*[[Domestic fish consumption of the pregnant women in Finland|Domestic fish consumption of the pregnant women in Finland]]
*[[ERF of methyl mercury on intelligence quotient]]
+
*[[Domestic fish consumption of the general population in Finland|Domestic fish consumption of the general population in Finland]]
*[[ERF of omega-3 fatty acids on intelligence quotient]]
+
*[[Fish oil intake in Beneris|Fish oil intake in Beneris]]  
 +
*[[Methyl mercury intake from fish in Beneris|Methyl mercury intake from fish in Beneris]]
  
===Indices===
+
'''Population characteristics'''
 +
 
 +
*[[Body weight in Finland|Body weight in Finland]]
 +
 
 +
'''Exposure-response functions'''
 +
 
 +
*[[ERF of methyl mercury on intelligence quotient|ERF of methyl mercury on intelligence quotient]]
 +
*[[ERF of omega-3 fatty acids on intelligence quotient|ERF of omega-3 fatty acids on intelligence quotient]]
 +
 
 +
=== Indices ===
  
 
{| {{prettytable}}
 
{| {{prettytable}}
!Fish species
+
|-
|-----
+
! Fish species
|
+
|-
*Farmed_salmon(sea+inland)
+
|  
*Wild_salmon(sea)
+
*Farmed_salmon(sea+inland)  
*Herring_(sea)
+
*Wild_salmon(sea)  
*White_fish(sea)
+
*Herring_(sea)  
*Sprat(sea)
+
*White_fish(sea)  
*Perch(sea)
+
*Sprat(sea)  
*Flounder(sea)
+
*Perch(sea)  
*Pike-perch(sea)
+
*Flounder(sea)  
*Bream(sea)
+
*Pike-perch(sea)  
*Pike(sea)
+
*Bream(sea)  
*Vendace(sea)
+
*Pike(sea)  
*Burbot(sea)
+
*Vendace(sea)  
*Wild_salmon(inland)
+
*Burbot(sea)  
*White_fish(inland)
+
*Wild_salmon(inland)  
*Perch(inland)
+
*White_fish(inland)  
*Pike-perch(inland)
+
*Perch(inland)  
*Bream(inland)
+
*Pike-perch(inland)  
*Pike(inland)
+
*Bream(inland)  
*Vendace(inland)
+
*Pike(inland)  
 +
*Vendace(inland)  
 
*Burbot(inland)
 
*Burbot(inland)
 +
 
|}
 
|}
  
 +
<br>
 +
 +
=== Analyses  ===
 +
 +
Interesting population subgroups for exposure might be:
 +
 +
*pregnant women with high fish consumption (e.g. 0.95 percentile of fish consumption data of pregnant women)
 +
*pregnant women with average fish consumption (e.g. mean fish consumption of pregnant women)
 +
*pregnant women with very low or no fish consumption (e.g. 0.05 percentile of fish consumption data of pregnant women)
 +
*general Finnish population with normal fish consumption (as a comparison to the pregnant women scenarios)
  
===Analyses ===
+
== Result  ==
  
Interesting population subgroups for exposure might be:
+
=== Results  ===
* pregnant women with high fish consumption (e.g. 0.95 percentile of fish consumption data of pregnant women)
 
* pregnant women with average fish consumption (e.g. mean fish consumption of pregnant women)
 
* pregnant women with very low or no fish consumption (e.g. 0.05 percentile of fish consumption data of pregnant women)
 
* general Finnish population with normal fish consumption (as a comparison to the pregnant women scenarios)
 
  
==Result==
+
=== Conclusions  ===
  
===Results===
+
{{assessment}}
  
===Conclusions ===
+
[[Category:Risk_assessments]]

Revision as of 11:27, 13 March 2009

The Analytica model file contains the actual calculations for this assessment. The actual code created with the ana-wiki converter can be found from [1].

Scope

Purpose

This assessment evaluates the effects of methyl mercury and omega-3 fatty acids on development of IQ in children. The source of exposure is Finnish fish consumption.

Boundaries

  • Population of Finland
  • Current situation


Scenarios

This study is a business-as-usual, i.e. a burden-of-disease assessment with only one decision scenario. D↷

This project is supposed to serve as a case study to represent the utilization of the pyrkilo method.

Intended users

Participants

  • Beneris researchers

Definition

Decision variables

  • None

Indicators

Other variables

Environmental variables

Exposure variables

Population characteristics

Exposure-response functions

Indices

Fish species
  • Farmed_salmon(sea+inland)
  • Wild_salmon(sea)
  • Herring_(sea)
  • White_fish(sea)
  • Sprat(sea)
  • Perch(sea)
  • Flounder(sea)
  • Pike-perch(sea)
  • Bream(sea)
  • Pike(sea)
  • Vendace(sea)
  • Burbot(sea)
  • Wild_salmon(inland)
  • White_fish(inland)
  • Perch(inland)
  • Pike-perch(inland)
  • Bream(inland)
  • Pike(inland)
  • Vendace(inland)
  • Burbot(inland)


Analyses

Interesting population subgroups for exposure might be:

  • pregnant women with high fish consumption (e.g. 0.95 percentile of fish consumption data of pregnant women)
  • pregnant women with average fish consumption (e.g. mean fish consumption of pregnant women)
  • pregnant women with very low or no fish consumption (e.g. 0.05 percentile of fish consumption data of pregnant women)
  • general Finnish population with normal fish consumption (as a comparison to the pregnant women scenarios)

Result

Results

Conclusions