Benefit-risk assessment of fish consumption for Beneris

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Scope

Net health effects of fish consumption D↷

Net health effects of fish consumption due to intake of beneficial nutrients and constituents and on the other hand, exposure to environmental contaminants taken up by fish. This assessment also evaluates the effects of methyl mercury and omega-3 fatty acids on development of IQ in children.


Definition

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Boundaries

  • Environmental contaminants relevant from the human health point of view and thus included in the assessment are:
    • polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F)
    • polychlorinated biphenyls (PCB)
    • mercury as methyl mercury (MetHg)
  • Nutritional constituents relevant from the human health point of view include a wide variety of effects and can be viewed from Benefit-risk assessment of fish and related policy options under title "Health consequences attributable to fish consumption". However, readily usable beneficial constituents with quantitative dose-response information available included in the assessment are:
    • omega-3 polyunsaturated fatty acids (PUFA)
    • iodine (I)
    • selenium (Se)
  • Current situation (BAU)


Beneris population

The Beneris population is defined as the general population (all age groups, all socioeconomic groups) in

  • Finland
  • Ireland
  • Spain
  • Denmark

Scenarios

BAU-type assessment (business-as-usual assessment), i.e. a burden-of-disease assessment with only one decision scenario. D↷

Intended users

Experts, researchers and decision makers in the field of environmental health, anyone interested and concerned with beneficial and hazardous constituents in fish species in the markets.

Participants

Participation basically completely open. Some parts containing original data will be protected.

  • Everyone interested
  • Beneris researchers (full access to the protected parts)

Variables

  • Decision variables: None at the moment D↷
  • Indicators: See health effect variables in the table below
  • Other variables: See table
Population characteristics Socio-economic status in Beneris | Smoking status in Beneris | Body weight in Finland | Baseline intelligence quotient (IQ) score in children | Baseline remaining lifetime risk of CVD death in adults | Baseline remaining lifetime risk of cancer in adults
Environmental variables Concentrations of beneficial nutrients in fish | Mercury and methyl mercury concentrations in fish | Concentrations of PCDD/Fs in fish | Concentrations of PCBs in fish
Exposure variables Fish oil intake in Beneris | Selenium intake from fish in Beneris | Methyl mercury intake from fish in Beneris | Iodine intake from fish in Beneris | Intake of PCB from fish in Beneris | Intake of PCDD/F from fish in Beneris | Domestic fish consumption of the general population in Finland | Domestic fish consumption of the pregnant women in Finland | Baseline intake of PCDD/F from fish in Beneris | Baseline intake of PCB from fish in Beneris
Exposure-response functions ERF of omega-3 fatty acids on intelligence quotient | ERF of omega-3 fatty acids on CVD risk in adults | Variable:Exposure-response of Se intake for IQ change in children | Variable:Exposure-response of Se intake for MI risk in adults | ERF of methyl mercury on intelligence quotient | ERF of methyl mercury on myocardial infarction | ERF of methyl mercury on CVD risk in adults | Variable:Exposure-response of iodine intake for IQ change in children | Variable:Exposure-response of PCB intake for dental aberrations risk in childrenERF of PCB on cancer | Variable:Exposure-response of PCDD/F intake for dental aberrations risk in children | ERF of dioxin on cancer | Variable:Exposure-response of PCDD/F intake for cancer risk in adults | Variable:Exposure-response of MeHg and Se interaction for IQ change in children | Variable:Exposure-response of MeHg and Se interaction for MI risk in adults
Health effect variables Variable:Risk for dental aberrations in children | Net health effects in Beneris | Intelligence quotient (IQ) in children in Beneris | Remaining lifetime risk of CVD death in adults | Remaining lifetime risk of cancer in adults


Nutritional benefits and risks of PCDD/F exposure of fish consumption in Finnish children and adults Analytica model
Beneris:Risk assessment of MeHg and n-3 fatty acids in fish
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Indexes

Fish species
  • Baltic herring (Clupea harengus membras)
  • Herring (Clupea harengus)
  • Vendace (Coregonus albula)
  • Whitefish (Coregonus lavaretus)
  • Pike (Esox lucius)
  • Rainbow trout (Onchorhynchus mykiss)
  • Shrimp (Pandalus sp.)
  • Perch (Perca fluviatilis)
  • Saithe (Pollachius virens)
  • Atlantic salmon (Salmo salar)
  • Pike-perch (Sander lucioperca)
  • Tuna (Thunnus thynnus)
Nutrients
  • Omega-3 fatty acids
  • Selenium
  • Iodine


  • Vitamin D
  • Vitamin E
  • Group B vitamins


Age categorizations were chosen in order to describe health effects of fish consumption in infants (0-2 years, this class includes prenatal period as well), adolescent (2-18 years), adults (18-55 years) and elderly people (55-).

Age categories (years)
  • 0 - 2
  • 2 - 18
  • 18 - 55
  • 55 -

Data

Causality

Unit

Formula

Result

See also

References