Difference between revisions of "Benefit-risk assessment of fish consumption for Beneris"
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*Indicators: See health effect variables in the table below | *Indicators: See health effect variables in the table below | ||
*Other variables: See table | *Other variables: See table | ||
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{| {{prettytable}} | {| {{prettytable}} | ||
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! Population characteristics | ! Population characteristics | ||
| − | | [[ | + | | [[Body weight in Finland|Body weight in Finland]]| [[Height in Finland]]| [[Baseline intelligence quotient (IQ) score in children|Baseline intelligence quotient (IQ) score in children]] | <span style="text-decoration: underline;"></span> |
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! Environmental variables | ! Environmental variables | ||
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! Exposure variables | ! Exposure variables | ||
| − | | [[Fish oil intake in Beneris|Fish oil intake | + | | [[Fish oil intake in Beneris|Fish oil intake in Beneris]] | [[Methyl mercury intake from fish in Beneris|Methyl mercury intake from fish in Beneris]] | [[Iodine intake from fish in Beneris|Iodine intake from fish in Beneris]] | [[Intake of PCB from fish in Beneris|Intake of PCB from fish in Beneris]] | [[Intake of PCDD/F from fish in Beneris|Intake of PCDD/F from fish in Beneris]] | [[Domestic fish consumption of the general population in Finland|Domestic fish consumption of the general population in Finland]] | [[Domestic fish consumption of the pregnant women in Finland|Domestic fish consumption of the pregnant women in Finland]] | |
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! Exposure-response functions | ! Exposure-response functions | ||
| − | | [[ERF of omega-3 fatty acids on intelligence quotient|ERF of omega-3 fatty acids on intelligence quotient]] | [[ERF of omega-3 fatty acids on CVD risk in adults|ERF of omega-3 fatty acids on CVD risk in adults]]<span style="text-decoration: underline;"></span> | + | | [[ERF of omega-3 fatty acids on intelligence quotient|ERF of omega-3 fatty acids on intelligence quotient]] | [[ERF of omega-3 fatty acids on CVD risk in adults|ERF of omega-3 fatty acids on CVD risk in adults]]<span style="text-decoration: underline;"></span> | [[ERF of methyl mercury on intelligence quotient|ERF of methyl mercury on intelligence quotient]] | [[ERF of methyl mercury on myocardial infarction|ERF of methyl mercury on myocardial infarction]] | [[ERF of methyl mercury on CVD risk in adults|ERF of methyl mercury on CVD risk in adults]] | [[Variable:Exposure-response of iodine intake for IQ change in children|Variable:Exposure-response of iodine intake for IQ change in children]] | [[Variable:Exposure-response of PCB intake for dental aberrations risk in children|Variable:Exposure-response of PCB intake for dental aberrations risk in children]] | [[ERF of PCB on cancer|ERF of PCB on cancer]] | [[Variable:Exposure-response of PCDD/F intake for dental aberrations risk in children|Variable:Exposure-response of PCDD/F intake for dental aberrations risk in children]] | [[ERF of dioxin on cancer|ERF of dioxin on cancer]] | [[Variable:Exposure-response of PCDD/F intake for cancer risk in adults|Variable:Exposure-response of PCDD/F intake for cancer risk in adults]] | |
|- | |- | ||
! Health effect variables | ! Health effect variables | ||
| − | | [[Variable:Risk for dental aberrations in children|Variable:Risk for dental aberrations in children]] | [[Net health effects in Beneris|Net health effects in Beneris]] | [[Intelligence quotient (IQ) in children in Beneris|Intelligence quotient (IQ) in children in Beneris]] | | + | | [[Variable:Risk for dental aberrations in children|Variable:Risk for dental aberrations in children]] | [[Net health effects in Beneris|Net health effects in Beneris]] | [[Intelligence quotient (IQ) in children in Beneris|Intelligence quotient (IQ) in children in Beneris]] | <br> |
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| − | [[Image:Valikaavio RBA Fish PCDDs A vs. C 25102007 ak.PNG|thumb|600px|center]] | + | [[Image:Valikaavio RBA Fish PCDDs A vs. C 25102007 ak.PNG|thumb|600px|center]] |
=== Indexes === | === Indexes === | ||
Revision as of 12:01, 27 May 2009
This page is a assessment.
The page identifier is Op_en1781 |
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| Moderator: [[category:Moderator:Olli]][[user:Olli|Olli]] [[moderators#Olli|(see all)]] |
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Contents
Scope
Net health effects of fish consumption due to intake of beneficial nutrients and constituents and on the other hand, exposure to environmental contaminants taken up by fish. D↷
Boundaries
- Environmental contaminants relevant from the human health point of view and thus included in the assessment are:
- polychlorinated dibenzo-p-dioxins and dibenzofurans (PCDD/F),
- polychlorinated biphenyls (PCB),
- mercury as methyl mercury (MeHg),
- Nutritional constituents relevant from the human health point of view include a wide variety of effects and can be viewed from Benefit-risk assessment of fish and related policy options under title "Health consequences attributable to fish consumption". However, readily usable beneficial constituents with quantitative dose-response information available included in the assessment are:
- omega-3 polyunsaturated fatty acids (PUFA): EPA and DHA,
- iodine (I),
- Health effects of fish consumption used in the assessment encompass neurological effects during early development, developmental dental defects, cardiovascular disease and cancer. In particular, the following health effects are considered:
- the effect of prenatal exposure to MeHg and omega-3 fatty acids on childhood cognitive development (IQ),
- the effect of exposure to dioxins and PCBs during early childhood on developmental dental defects (defects of enamel in permanent teeth or missing of smaller molars),
- the effect of exposure to MeHg and omega-3 fatty acids in adulthood on cardiovascular disease,
- the effect of exposure to dioxins and PCBs on cancer.
- Beneris population - the Beneris population is defined as the general population (all age groups) in
- Finland,
- Ireland,
- Spain,
- Denmark.
Current assessment is performed based on Finnish conditions only.
- Current situation (BAU)
Scenarios
BAU-type assessment (business-as-usual assessment), i.e. a burden-of-disease assessment with only one decision scenario. D↷
Intended users
Experts, researchers and decision makers in the field of environmental health, anyone interested and concerned with beneficial and hazardous constituents in fish species in the markets.
Participants
Participation basically completely open. Some parts containing original data will be protected.
- Everyone interested
- Beneris researchers (full access to the protected parts)
Definition
Variables
- Decision variables: None at the moment D↷
- Indicators: See health effect variables in the table below
- Other variables: See table
| Nutritional benefits and risks of PCDD/F exposure of fish consumption in Finnish children and adults Analytica model |
| Beneris:Risk assessment of MeHg and n-3 fatty acids in fish |
Indexes
| Fish species |
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| Nutrients |
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Age categorizations were chosen in order to describe health effects of fish consumption in infants (0-2 years, this class includes prenatal period as well), adolescent (2-18 years), adults (18-55 years) and elderly people (55-).
| Age categories (years) |
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